(R)-N-(4-chlorobenzylidene)-2-methylpropane-2-sulfinamide - Names and Identifiers
(R)-N-(4-chlorobenzylidene)-2-methylpropane-2-sulfinamide - Physico-chemical Properties
| Molecular Formula | C11H14ClNOS
|
| Molar Mass | 243.75 |
| Density | 1.17±0.1 g/cm3(Predicted) |
| Boling Point | 361.9±44.0 °C(Predicted) |
| pKa | -0.42±0.50(Predicted) |
(R)-N-(4-chlorobenzylidene)-2-methylpropane-2-sulfinamide - Upstream Downstream Industry
(R)-N-(4-chlorobenzylidene)-2-methylpropane-2-sulfinamide - Introduction
(R)-N-(4-chlorobenzylidene)-2-methylpropane-2-sulfinamide is an organic compound whose structure contains an acidophilic navel orange (iminosulfur group) and a chlorobenzyl group. The following is a detailed description of the properties, uses, preparation and safety information of the compound:
Nature:
-Appearance:(R)-N-(4-chlorobenzylidene)-2-methylpropane-2-sulfinamide is a white to yellow crystalline solid.
-Solubility: It is soluble in many organic solvents, such as methanol, chloroform and dichloromethane, but almost insoluble in water.
Use:
- (R)-N-(4-chlorobenzylidene)-2-methylpropane-2-sulfinamide is commonly used as a chiral pharmaceutical intermediate, especially for the synthesis of chiral compounds.
-It can also be used as a ligand for transition metal catalysts.
Method:
The preparation of- (R)-N-(4-chlorobenzylidene)-2-methylpropane-2-sulfinamide is generally accomplished by chemical synthesis. A specific method can be used to react benzyl alcohol with P-chlorobenzoyl chloride to obtain p-chlorobenzyl ketone. The p-chlorobenzylketone is then reacted with dimethyl sulfoxide (DMSO) to produce (R)-N-(4-chlorobenzylidene)-2-methylpropane-2-sulfinamide.
Safety Information:
- (R)-N-(4-chlorobenzylidene)-2-methylpropane-2-sulfinamide has good safety under normal use conditions.
-But it is an organic compound, and care should be taken to avoid contact with skin, eyes and inhalation.
-Take appropriate personal protective measures during use, handling and storage, such as wearing chemical protective glasses, gloves and gas masks.
-When handling this compound, observe the safety procedures for chemicals and properly dispose of waste.
Last Update：2024-04-09 02:00:51