(R)-N-Boc-2-Methoxycarbonyl-4-pyrrolidone - Names and Identifiers
(R)-N-Boc-2-Methoxycarbonyl-4-pyrrolidone - Physico-chemical Properties
Molecular Formula | C11H17NO5
|
Molar Mass | 243.26 |
Density | 1.209 |
Melting Point | 42-46℃ |
Boling Point | 333.1±42.0 °C(Predicted) |
Flash Point | 155.283°C |
Vapor Presure | 0mmHg at 25°C |
Appearance | White to brown powder or solid |
pKa | -3.86±0.40(Predicted) |
Storage Condition | under inert gas (nitrogen or Argon) at 2-8°C |
Refractive Index | 1.488 |
MDL | MFCD01861778 |
(R)-N-Boc-2-Methoxycarbonyl-4-pyrrolidone - Risk and Safety
Hazard Symbols | Xn - Harmful
|
Risk Codes | R20/21/22 - Harmful by inhalation, in contact with skin and if swallowed.
R41 - Risk of serious damage to eyes
|
Safety Description | S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.
S36/37 - Wear suitable protective clothing and gloves.
S39 - Wear eye / face protection.
|
Hazard Class | IRRITANT |
(R)-N-Boc-2-Methoxycarbonyl-4-pyrrolidone - Introduction
BOC-4-oxo-L-proline methyl ester is an organic compound. Its molecular formula is C12H19NO6, and its structure contains an oxoproline group and a methyl ester group.
BOC-4-oxo-L-proline methyl ester is mainly used as a protecting group reagent in organic synthesis reactions. It can react with amino acids and other compounds to form a protecting group, which is used to protect the amino group or hydroxyl group to prevent unnecessary side reactions in the reaction. After the reaction is complete, the protecting group can be removed by appropriate conditions to reveal the original functional group.
Preparation of BOC-4-oxo-L-proline methyl ester requires chemical synthesis. One common method of preparation is to react BOC-4-oxo-L-proline with methyl formate to produce BOC-4-oxo-L-proline methyl ester.
The preparation process can have higher yield and selectivity.
BOC-4-oxo-L-proline methyl ester has high safety, but as an organic compound, it is still necessary to pay attention to follow good laboratory practices. Avoid touching it with skin or eyes and wear protective equipment if necessary. Avoid high temperatures, fire sources and strong oxidants during storage. Proper management and disposal of BOC-4-oxo-L-proline methyl ester waste and solvents to comply with relevant regulations.
Last Update:2024-04-10 22:29:15