(R)-N-Boc-3-(aminomethyl)pyrrolidine

(R)-N-Boc-3-(aminomethyl)pyrrolidine - Names and Identifiers

Name	(R)-N-Boc-3-(aminomethyl)pyrrolidine
Synonyms	(3R)-3-Aminomethyl-1-Boc-pyrrolidine (R)-N-Boc-3-(aminomethyl)pyrrolidine (r)-n-boc-3-(aminomethyl)pyrrolidine (R)-1-N-BOC-3-(Aminomethyl)Pyrrolidine (R)-1-N-BOC-3-(AMINOMETHYL)PYRROLIDINE (3R)-3-(Aminomethyl)pyrrolidine, N1-BOC protected (R)-tert-butyl 3-(aminomethyl)pyrrolidine-1-carboxylate (R)-Tert-BUTYL-3-(Aminomethyl)Pyrrolidine-1-CARBOXYLATE (R)-TERT-BUTYL-3-(AMINOMETHYL)PYRROLIDINE-1-CARBOXYLATE tert-butyl (3R)-3-(aminomethyl)pyrrolidine-1-carboxylate 3(R)-Aminomethyl-Pyrrolidine-1-Carboxylic Acid Tert-BUTYL ESTER (R)-3-Aminomethyl-Pyrrolidine-1-Carboxylic Acid Tert-BUTYL ESTER (R)-3-AMINOMETHYL-PYRROLIDINE-1-CARBOXYLIC ACID TERT-BUTYL ESTER tert-butyl (3R)-3-(aminomethyl)pyrrolidine-1-carboxylate hydrochloride tert-Butyl (3R)-3-(aminomethyl)pyrrolidine-1-carboxylate, (3R)-3-(Aminomethyl)-1-(tert-butoxycarbonyl)pyrrolidine
CAS	199174-29-3
InChI	InChI=1/C10H20N2O2.ClH/c1-10(2,3)14-9(13)12-5-4-8(6-11)7-12;/h8H,4-7,11H2,1-3H3;1H/t8-;/m1./s1
InChIKey	OGCCBDIYOAFOGK-MRVPVSSYSA-N

(R)-N-Boc-3-(aminomethyl)pyrrolidine - Physico-chemical Properties

Molecular Formula	C10H20N2O2
Molar Mass	200.28
Density	1.044±0.06 g/cm3(Predicted)
Boling Point	280.3±13.0 °C(Predicted)
Flash Point	144.5°C
Vapor Presure	0.000323mmHg at 25°C
Appearance	Liquid
Color	Colorless to yellow
BRN	10537871
pKa	10.12±0.29(Predicted)
Storage Condition	2-8°C
Sensitive	Air Sensitive
Refractive Index	1.4780

(R)-N-Boc-3-(aminomethyl)pyrrolidine - Risk and Safety

Hazard Symbols	Xn - Harmful
Risk Codes	R36/37/38 - Irritating to eyes, respiratory system and skin. R36 - Irritating to the eyes R22 - Harmful if swallowed
Safety Description	S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. S36/37/39 - Wear suitable protective clothing, gloves and eye/face protection.
WGK Germany	3
TSCA	No

(R)-N-Boc-3-(aminomethyl)pyrrolidine - Introduction

(R)-N-Boc-3-(aminomethyl)pyrrolidine is an organic compound with the following properties:

1. Appearance: (R)-N-Boc-3-(aminomethyl)pyrrolidine is a white solid.

2. Solubility: (R)-N-Boc-3-(aminomethyl)pyrrolidine has good solubility in common organic solvents.

3. Stability: (R)-N-Boc-3-(aminomethyl)pyrrolidine is relatively stable under regular experimental conditions, but it may decompose under high temperature, oxidant or strong acid conditions.

4. Use: (R)-N-Boc-3-(aminomethyl)pyrrolidine is an important organic synthesis intermediates, commonly used in the synthesis of drugs, pesticides and other organic compounds. It can be used as a chiral reagent for the preparation of chiral target compounds.

5. Preparation method: (R)-N-Boc-3-(aminomethyl)pyrrolidine preparation method is more complex, the common method is the nucleophilic substitution reaction of pyrrolidine and ethyl carbamate with 1-butoxycarbonylcyclobutane.

6. Safety Information: (R)-N-Boc-3-(aminomethyl)pyrrolidine is generally less toxic under proper use and storage conditions. However, appropriate safety measures should still be taken, such as wearing protective gloves and glasses to avoid inhalation or contact with skin. When handling and disposing, follow local regulations.

Last Update：2024-04-09 20:45:29