(R)-baclofen

Name	(R)-baclofen
Synonyms	STX 209 l-Baclofen D-Baclofen (R)-baclofen (R)-Baclofen (-)-Baclofen R-(-)-Baclofen UNII-NYU6UTW25B (R)-(-)-Baclofen 4-azanyl-3-(4-chlorophenyl)butanoic acid (R)-4-Amino-3-(4-chlorophenyl)butyric acid (R)-4-Amino-3-(4-chlorophenyl)butanoic acid (3R)-4-amino-3-(4-chlorophenyl)butanoic acid (βR)-β-(AMinoMethyl)-4-chlorobenzenepropanoic Acid Benzenepropanoic acid, b-(aMinoMethyl)-4-chloro-, (bR)- Benzenepropanoic acid, β-(aminomethyl)-4-chloro-, (βR)- Benzenepropanoic acid, beta-(aminomethyl)-4-chloro-, (R)- Benzeneporopanoic acid, (beta-(aminomethyl)-4-chloro-, (betaR)-
CAS	69308-37-8
InChI	InChI=1/C10H12ClNO2/c11-9-3-1-7(2-4-9)8(6-12)5-10(13)14/h1-4,8H,5-6,12H2,(H,13,14)/t8-/m0/s1

Molecular Formula	C10H12ClNO2
Molar Mass	213.66
Density	1.285±0.06 g/cm3(Predicted)
Melting Point	171-174°C
Boling Point	364.3±32.0 °C(Predicted)
Flash Point	174.1°C
Vapor Presure	6.01E-06mmHg at 25°C
pKa	4.04±0.10(Predicted)
Storage Condition	Keep in dark place,Inert atmosphere,Room temperature
Refractive Index	1.576
In vivo study	(R)-Baclofen (STX209) suppresses audiogenic seizures in the Fmr1 -knockout mouse on the seizure-resistant C57BL/6 background with an effective dose of 1 mg/kg . Acute intraperitoneal administration of (R)-Baclofen (STX209) significantly reduces the percent of mice displaying seizures (seizure incidence), with a minimum effective dose (MED) of 1.5 mg/kg.