(R)-beta-(4-Bromophenyl)alanine

(R)-beta-(4-Bromophenyl)alanine - Names and Identifiers

Name	(R)-3-Amino-3-(4-bromophenyl)propionic acid
Synonyms	H-D-b-Phe(4-Br)-OH -R-4-Bromophenylalanine ?-R-4-Bromophenylalanine (R)-beta-(4-Bromophenyl)alanine (R)-3-(P-BROMOPHENYL)-BETA-ALANINE D-3-Amino-3-(4-bromo)propanoic acid (βR)-β-amino-4-bromo-Benzenepropanoic acid (R)-3-Amino-3-(4-bromophenyl)propionic acid
CAS	479074-63-0
InChI	InChI=1/C9H10BrNO2/c10-7-3-1-6(2-4-7)8(11)5-9(12)13/h1-4,8H,5,11H2,(H,12,13)/t8-/m1/s1

(R)-beta-(4-Bromophenyl)alanine - Physico-chemical Properties

Molecular Formula	C9H10BrNO2
Molar Mass	244.09
Density	1.585±0.06 g/cm3(Predicted)
Melting Point	258-260 °C(Solv: water (7732-18-5); acetone (67-64-1))
Boling Point	378.1±32.0 °C(Predicted)
Flash Point	182.5°C
Vapor Presure	2.17E-06mmHg at 25°C
pKa	3.62±0.10(Predicted)
Storage Condition	2-8°C(protect from light)
Refractive Index	1.607

(R)-beta-(4-Bromophenyl)alanine - Introduction

(R)-3-Amino-3-(4-bromophenyl)propionic acid is an organic compound with the chemical formula C9H10BrNO2 and a molecular weight of 246.09g/mol. It is a chiral compound with optical activity, and its optically active body is (R)-3-Amino-3-(4-bromophenyl)propionic acid.

(R)-3-Amino-3-(4-bromophenyl)propionic acid can be used as a pharmaceutical intermediate. It is often used in drug synthesis to synthesize biologically active molecules. In addition, it can also be used as a reagent and catalyst in organic synthesis.

A common method for preparing (R)-3-Amino-3-(4-bromophenyl)propionic acid is by halogenation of (R)-3-amino -3-(4-methoxyphenyl) propionic acid. The specific steps can be carried out as follows:
1. Reaction of (R)-3-amino -3-(4-methoxyphenyl) propionic acid with a halogenating reagent such as cuprous bromide (CuBr) or silver bromide (AgBr).
2. This is followed by alkali treatment, such as sodium carbonate (Na2CO3) or sodium hydroxide (NaOH), etc., to remove the methoxy group and obtain (R)-3-Amino-3-(4-bromophenyl)propionic acid.

Regarding safety information, since specific experimental conditions and operating methods are not provided, a detailed understanding of laboratory conditions and safety operating specifications is also required. Attention should be paid to personal protective measures, such as wearing appropriate protective gloves, glasses and laboratory coats, and operating in a well-ventilated environment. At the same time, correct waste treatment methods should be followed to avoid pollution to the environment. To ensure safety, please follow all relevant regulations and guidance documents, and carefully read the safety data sheet of any chemical before using it.

Last Update：2024-04-09 21:11:58