(R,S)-2-Amino-3-methyl-butyricacid
DL-Valine
CAS: 516-06-3
Molecular Formula: C5H11NO2
(R,S)-2-Amino-3-methyl-butyricacid - Names and Identifiers
| Name | DL-Valine |
| Synonyms | DL-VAL DL-Valine FEMA 3444 H-DL-VAL-OH H-DL-Val-OH Valine, DL- DL-α-Aminoisovaleric acid DL-alpha-Aminoisovaleric acid DL-2-Amino-3-methylbutyric acid (R,S)-2-Amino-3-methyl-butyricacid (±)-α-Aminoisovaleric acid, DL-2-Amino-3-methylbutanoic acid |
| CAS | 516-06-3 |
| EINECS | 208-220-0 |
| InChI | InChI=1/C5H11NO2/c1-3(2)4(6)5(7)8/h3-4H,6H2,1-2H3,(H,7,8) |
(R,S)-2-Amino-3-methyl-butyricacid - Physico-chemical Properties
| Molecular Formula | C5H11NO2 |
| Molar Mass | 117.15 |
| Density | 1.31 |
| Melting Point | 295 °C (dec.) (lit.) |
| Boling Point | 213.6±23.0 °C(Predicted) |
| Specific Rotation(α) | -0.6～+0.6° (20℃/D)(c=8, HCl) |
| Flash Point | 83°C |
| JECFA Number | 1426 |
| Water Solubility | 68 g/L |
| Solubility | Soluble in water, insoluble in cold ethanol, ether and acetone |
| Vapor Presure | 0.0633mmHg at 25°C |
| Appearance | White crystalline powder |
| Color | White |
| Odor | Odorless |
| Merck | 14,9909 |
| BRN | 506689 |
| pKa | pK1:2.32(+1);pK2:9.61(0) (25°C) |
| Storage Condition | Keep in dark place,Inert atmosphere,Room temperature |
| Sensitive | Easily absorbing moisture |
| Refractive Index | 1.4650 (estimate) |
| MDL | MFCD00004267 |
| Physical and Chemical Properties | density 1.31 melting point 283.5-285°C water-soluble 68g/L |
| Use | Can be used for nutritional and pharmaceutical synthesis |
(R,S)-2-Amino-3-methyl-butyricacid - Risk and Safety
| Hazard Symbols | Xn - Harmful |
| Risk Codes | 40 - Limited evidence of a carcinogenic effect |
| Safety Description | S22 - Do not breathe dust. S24/25 - Avoid contact with skin and eyes. S36 - Wear suitable protective clothing. |
| WGK Germany | 3 |
| RTECS | YV9355500 |
| TSCA | Yes |
| HS Code | 29224995 |
(R,S)-2-Amino-3-methyl-butyricacid - Reference
| Reference Show more | 1. [IF=5.833] Yang Xuan et al."Open-tubular capillary electrochromatography with β-cyclodextrin-functionalized magnetic nanoparticles as stationary phase for enantioseparation of dansylated amino acids."Microchim Acta. 2019 Apr;186(4):1-8 2. [IF=4.759] Jingtang Li et al."Synthesis and application of ionic liquid functionalized β-cyclodextrin, mono-6-deoxy-6-(4-amino-1,2,4-triazolium)-β-cyclodextrin chloride, as chiral selector in capillary electrophoresis."J Chromatogr A. 2018 Jul;1559:178 3. [IF=4.556] Dandan Zhao et al."Physico-chemical properties and free amino acids profiles of six wolfberry cultivars in Zhongning."J Food Compos Anal. 2020 May;88:103460 4. [IF=4.379] Feng Lin et al."Chemical profile changes during pile fermentation of Qingzhuan tea affect inhibition of α-amylase and lipase."Sci Rep-Uk. 2020 Feb;10(1):1-10 5. [IF=4.35] Xiaomei Dai et al."1-Methylcyclopropene Preserves the Quality of Chive (Allium schoenoprasum L.) by Enhancing Its Antioxidant Capacities and Organosulfur Profile during Storage."Foods. 2021 Aug;10(8):1792 6. [IF=3.361] Ning Zhao et al."Ratiometric fluorescence probe of Cu2+ and biothiols by using carbon dots and copper nanoclusters."Rsc Adv. 2021 Oct;11(53):33662-33674 7. [IF=4.242] Hang Yang et al."Dietary leucine requirement of juvenile largemouth bass (Micropterus salmoides) based on growth, nutrient utilization and growth-related gene analyses."Aquaculture. 2022 Jun;555:738207 8. [IF=3.463] Xiaomei Dai et al."S-alk(en)ylcysteine sulfoxides biosynthesis and free amino acids profile in different parts of postharvest chive (Allium schoenoprasum L.)."SCIENTIA HORTICULTURAE. 2022 Sep;303:111191 |
(R,S)-2-Amino-3-methyl-butyricacid - Introduction
It can sublimate when heated at a general speed and decompose at 298 ℃ (tube sealing, rapid heating). Solubility in water: 68g/l, actually insoluble in cold alcohol and ether, soluble in inorganic acid; insoluble in organic solvents; slightly soluble in benzene and alcohol.
Last Update：2022-10-16 17:25:46
(R,S)-2-Amino-3-methyl-butyricacid - Reference Information
| FEMA | 3444 | D,L-VALINE |
| NIST chemical information | Information provided by: webbook.nist.gov (external link) |
| EPA chemical information | Information provided by: ofmpub.epa.gov (external link) |
| use | for biochemical research. Used as biochemical reagents, etc. Can be used for nutrient and drug synthesis |
| production method | ammonium chloride, potassium cyanide and concentrated ammonia water are mixed, newly steamed isobutyraldehyde is added under stirring for reaction, reactants are extracted with ether, activated carbon is treated with hydrochloric acid, ethanol is refluxed, pyridine is added to precipitate DL-valine, and the product is obtained by washing with ethanol. |
Last Update：2024-04-09 20:45:29
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Multiple SpecificationsSpot supply
Product Name: DL-Valine Visit Supplier Webpage Request for quotationCAS: 516-06-3
Tel: 18301782025
Email: 3008007409@qq.com
Mobile: 18021002903
QQ: 3008007409
Wechat: 18301782025
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