(RS)-Mcpg

Name	(RS)-Mcpg
Synonyms	(RS)-MCPG (RS)-Mcpg (RS)-A-METHYL-4-CARBOXYPHENYLGLYCINE (±)-Α-METHYL-(4-CARBOXYPHENYL)GLYCINE (RS)-ALPHA-METHYL-4-CARBOXYPHENYLGLYCINE (+-)-A-METHYL-4-CARBOXYPHENYLGLYCINE MET ABOTROPIC GLUTAMAT
CAS	146669-29-6

Molecular Formula	C10H11NO4
Molar Mass	209.2
Density	1.390±0.06 g/cm3(Predicted)
Boling Point	425.3±40.0 °C(Predicted)
pKa	1.76±0.10(Predicted)
Storage Condition	Keep in dark place,Inert atmosphere,Room temperature
In vitro study	MCPG can block group I (mGluR1 and mGluR5) and group II receptors (mGluR2 and mGluR3).
In vivo study	(RS)-MCPG (alpha-MCPG; 500 μM) blocks the TBS-induced shifts in EGABA in either juvenile or neonatal neurons. Pretreatment with the low dose of (RS)-MCPG (25 nM; i.c.; daily; 5 days) significantly attenuates amphetamine-induced locomotor activity in 10-day-old male and female rats of Sprague-Dawley descent.

WGK Germany

Last Update：2024-01-02 23:10:35

biological activity	(RS)-MCPG (alpha-MCPG) it is a competitive and selective group I/II metabotropic glutamate receptor (mGluR) antagonist. (RS)-MCPG blocks TBS-induced conversion of hippocampal neurons in young and neonatal rats.
Target	group I/group II mGluR

Last Update：2024-04-09 02:00:14

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(RS)-Mcpg

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