(S)-(+)-1-(2-Pyrrolidinylmethyl)pyrrolidine

(S)-(+)-1-(2-Pyrrolidinylmethyl)pyrrolidine - Names and Identifiers

Name	(S)-(+)-1-(2-pyrrolidinylmethyl)-pyrrolidine
Synonyms	1-(pyrrolidin-2-ylmethyl)pyrrolidine 1-[(2S)-pyrrolidin-2-ylmethyl]pyrrolidine (S)-(-)-1-(2-PYRROLIDINYLMETHYL)PIPERIDINE 1-(((S)-pyrrolidin-2-yl)methyl)pyrrolidine (S)-(+)-1-(2-Pyrrolidinylmethyl)pyrrolidine (S)-(+)-1-(2-PYRROLIDINYLMETHYL)PYRROLIDINE (S)-1-METHYL-2-(PIPERIDINOMETHYL)PYRROLIDINE (S)-(+)-1-(2-pyrrolidinylmethyl)-pyrrolidine (S)-(-)-1-METHYL-2-(1-PIPERIDINOMETHYL)PYRROLIDINE (S)-2-(1-Pyrrolidinylmethyl)pyrrolidine dihydrochloride
CAS	51207-66-0
InChI	InChI=1/C9H18N2/c1-2-7-11(6-1)8-9-4-3-5-10-9/h9-10H,1-8H2/t9-/m0/s1
InChIKey	YLBWRMSQRFEIEB-VIFPVBQESA-N

(S)-(+)-1-(2-Pyrrolidinylmethyl)pyrrolidine - Physico-chemical Properties

Molecular Formula	C9H18N2
Molar Mass	154.25
Density	0.946g/mLat 25°C(lit.)
Boling Point	99-101°C2mm Hg(lit.)
Flash Point	220°F
Vapor Presure	0.009mmHg at 25°C
Appearance	clear liquid
Color	Colorless to Light yellow
pKa	10.91±0.10(Predicted)
Storage Condition	Room Temprature
Refractive Index	n20/D 1.4871(lit.)
MDL	MFCD00013441

(S)-(+)-1-(2-Pyrrolidinylmethyl)pyrrolidine - Risk and Safety

Risk Codes	R36/38 - Irritating to eyes and skin. R36/37/38 - Irritating to eyes, respiratory system and skin. R22 - Harmful if swallowed
Safety Description	S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. S36 - Wear suitable protective clothing.
UN IDs	NA 1993 / PGIII
WGK Germany	3
FLUKA BRAND F CODES	10-34
HS Code	29339900

(S)-(+)-1-(2-Pyrrolidinylmethyl)pyrrolidine - Introduction

(S)-(+)-1-(2-yrrolidinylmethyl)-pyrrolidine is an organic compound with the chemical formula C11H20N2, with chirality, and its (S)-(+)-enantiomer is often used in research and applications.

The main properties of (S)-( )-1-(2-pyrolidinylmethyl)-pyrrolidine are as follows:
1. appearance: colorless liquid or solid.
2. Solubility: Soluble in water, alcohols and ether organic solvents.
3. Melting point: about 40-42°C.
4. Ignition point: about 89°C.

(S)-( )-1-(2-pyrrolidinylmethyl)-pyrrolidine has many applications in chemical research and drug synthesis:
1. optical separation: can be used to separate enantiomers.
2. catalyst: can be used in organic reaction catalyst.
3. drug synthesis: can be used for the synthesis of drug intermediates.

A common method for preparing (S)-( )-1-(2-pyrrolidinylmethyl)-pyrrolidine is to react pyrrolidine and formaldehyde by condensation under alkaline conditions. The reaction is usually carried out in a suitable solvent and the desired product is obtained by reacting the base aldehyde salt formed in the intermediate with pyrrolidine.

Regarding safety information, the specific hazards of (S)-( )-1-(2-pyrrolidinylmethyl)-pyrrolidine depend on its use and operating conditions. It may be irritating and allergenic, so care should be taken to avoid inhalation, skin contact and ingestion during use. Wear appropriate personal protective equipment, such as protective gloves and masks, and consult professional safety instructions for better adaptability. During storage, it should be kept in a cool, dry, well-ventilated place, away from fire and oxidizing agents.

Last Update：2024-04-09 20:49:11