(S)-(+)-1-甲基-3-羟基吡咯烷

(S)-(+)-1-甲基-3-羟基吡咯烷 - Names and Identifiers

Name	(S)-(+)-1-Methyl-3-pyrrolidinol
Synonyms	CHEMPACIFIC 38130 (S)-1-METHYLPYRROLIDIN-3-OL (S)-N-Methyl-3-pyrrolidinol (S)-1-Methyl-3-pyrrolidinol (3S)-1-methylpyrrolidin-3-ol (R)-3-Hydroxy-1-methylpyr... (S)-(+)-1-Methyl-3-pyrrolidinol (S)-3-HYDROXY-1-METHYL-PYRROLIDINE (S)-(+)-Methyl-3-hydroxypyrrolidine (S)-(+)-1-Methyl-3-Hydroxypyrrolidine (S)-(+)-3-Hydroxy-N-METHYLPYRROLIDINE
CAS	104641-59-0
EINECS	677-547-2
InChI	InChI=1/C5H11NO/c1-6-3-2-5(7)4-6/h5,7H,2-4H2,1H3/t5-/m0/s1

(S)-(+)-1-甲基-3-羟基吡咯烷 - Physico-chemical Properties

Molecular Formula	C5H11NO
Molar Mass	101.15
Density	0.993g/mLat 25°C(lit.)
Boling Point	181-182°C(lit.)
Specific Rotation(α)	6 º (c=1%, chloroform)
Flash Point	192°F
Vapor Presure	0.132mmHg at 25°C
Appearance	Slightly yellow to slightly brown liquid
Color	Colorless to yellow to brown
BRN	4349394
pKa	14.95±0.20(Predicted)
Storage Condition	Keep in dark place,Sealed in dry,Room Temperature
Sensitive	Air Sensitive & Hygroscopic
Refractive Index	n20/D 1.4660(lit.)
MDL	MFCD03788748
Physical and Chemical Properties	Sensitivity: Air Sensitive & hygropic WGK Germany:3 RTECS:TM9570000

(S)-(+)-1-甲基-3-羟基吡咯烷 - Risk and Safety

Hazard Symbols	Xi - Irritant
Risk Codes	36/37/38 - Irritating to eyes, respiratory system and skin.
Safety Description	S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. S36 - Wear suitable protective clothing.
UN IDs	NA 1993 / PGIII
WGK Germany	3
RTECS	TM9570000
HS Code	29339900

(S)-(+)-1-甲基-3-羟基吡咯烷 - Reference Information

Use

(S)-( )-1-methyl-3-hydroxypyrrolidine is a useful synthetic intermediate. It is used to prepare diarylacylaminopyrimidines as adenosine A2A antagonists. It is also used in the synthesis of (alkoxyamino) (pyridylamino) pyrazinonitrile as a selective checkpoint kinase 1 (CHK1) inhibitor with oral antitumor activity.

Last Update：2024-04-10 22:29:15