(S)-(-)-2-Phenylglycinol - Names and Identifiers
(S)-(-)-2-Phenylglycinol - Physico-chemical Properties
Molecular Formula | C8H11NO
|
Molar Mass | 137.18 |
Density | 1.104±0.06 g/cm3(Predicted) |
Melting Point | 57-59°C |
Boling Point | 160°C/17mm |
Specific Rotation(α) | 43 º (c=2%, EtOH) |
Flash Point | 160°C/17mm |
Solubility | Soluble in methanol. |
Appearance | White powder |
BRN | 2412760 |
pKa | 12.04±0.35(Predicted) |
Storage Condition | It is sensitive to air and stored in a sealed way |
Stability | Stable. Incompatible with strong oxidizing agents. |
Sensitive | Air Sensitive |
MDL | MFCD00239405 |
(S)-(-)-2-Phenylglycinol - Risk and Safety
Risk Codes | R22 - Harmful if swallowed
R34 - Causes burns
|
Safety Description | S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.
S36/37/39 - Wear suitable protective clothing, gloves and eye/face protection.
S45 - In case of accident or if you feel unwell, seek medical advice immediately (show the label whenever possible.)
|
UN IDs | UN 3259 8/PG 3 |
WGK Germany | 3 |
FLUKA BRAND F CODES | 3-10-23-34 |
HS Code | 29221990 |
Hazard Note | Irritant |
Hazard Class | 8 |
Packing Group | III |
(S)-(-)-2-Phenylglycinol - Introduction
(S)-( )-2-Amino-1-phenylethanol is a chiral organic compound with a chemical formula of C8H11NO and a molecular weight of 137.18g/mol. It exists as two enantiomers, of which (S)-( )-2-Amino-1-phenylethanol is the dextrorotatory isomer.
(S)-( )-2-Amino-1-phenylethanol has the form of colorless or slightly yellow crystals or liquid. It has a pungent ammonia smell and can be dissolved in solvents such as water, alcohols and ether. It has a melting point of about 122-125°C and a boiling point of 184-186°C.
In the field of medicine and chemistry,(S)-( )-2-Amino-1-phenylethanol has a wide range of uses. It is often used as a chiral auxiliary in organic synthesis, which can catalyze or improve the enantioselectivity of the reaction. In addition, it can also be used as a raw material for the synthesis of antibiotics, hormones, pharmaceutical intermediates and pesticides.
The method for preparing (S)-( )-2-Amino-1-phenylethanol mainly includes synthesis through chiral pollution or chiral induction. One commonly used method is by the cleavage of malonic acid di-(p-tolyl)-nicotine amide by reaction with hydrogen.
When using (S)-( )-2-Amino-1-phenylethanol, you need to pay attention to its safety information. It has a certain degree of irritation and may have an irritating effect on the eyes, skin and mucous membranes. Therefore, in the operation should pay attention to wear protective glasses, gloves and protective clothing. At the same time, in the process of storage and handling, the relevant safety operation procedures should be strictly observed to ensure the safety of personnel. At the same time, avoid contact with oxidants and strong acids to avoid dangerous reactions.
Last Update:2024-04-09 21:11:58