(S)-(-)-4-(1-AMINOETHYL)TOLUENE
(S)-1-(4-Methylphenyl)ethylamine
CAS: 27298-98-2
Molecular Formula: C9H13N
(S)-(-)-4-(1-AMINOETHYL)TOLUENE - Names and Identifiers
| Name | (S)-1-(4-Methylphenyl)ethylamine |
| Synonyms | (S)-1-P-TOLYLETHANAMINE (S)-(-)-1-(p-Tolyl)ethylamine (S)-(-)-1-(P-TOLYL)ETHYLAMINE (S)-(-)-A-(P-TOLYL)ETHYLAMINE (S)-(-)-4-(1-AMINOETHYL)TOLUENE (S)-alpha,p-Dimethylbenzylamine (S)-1-(4-Methylphenyl)ethylamine (S)-1-(4-METHYLPHENYL)ETHYLAMINE (1R)-1-(4-methylphenyl)ethanamine (1S)-1-(4-methylphenyl)ethanamine (S)-(-)-ALPHA,4-DIMETHYLBENZYLAMINE (S)-(-)-1-(4-METHYLPHENYL)ETHYLAMINE (S)-4-METHYL-ALPHA-METHYLBENZYLAMINE |
| CAS | 27298-98-2 |
| EINECS | 623-635-0 |
| InChI | InChI=1/C9H13N/c1-7-3-5-9(6-4-7)8(2)10/h3-6,8H,10H2,1-2H3/t8-/m0/s1 |
| InChIKey | UZDDXUMOXKDXNE-QMMMGPOBSA-N |
(S)-(-)-4-(1-AMINOETHYL)TOLUENE - Physico-chemical Properties
| Molecular Formula | C9H13N |
| Molar Mass | 135.21 |
| Density | 0.919g/mLat 25°C(lit.) |
| Boling Point | 205°C(lit.) |
| Specific Rotation(α) | -37 º (NEAT) |
| Flash Point | 180°F |
| Vapor Presure | 0.212mmHg at 25°C |
| Specific Gravity | 0.919 |
| BRN | 2422644 |
| pKa | 9.20±0.10(Predicted) |
| Storage Condition | under inert gas (nitrogen or Argon) at 2-8°C |
| Sensitive | Air Sensitive |
| Refractive Index | n20/D 1.521(lit.) |
(S)-(-)-4-(1-AMINOETHYL)TOLUENE - Risk and Safety
| Hazard Symbols | C - Corrosive |
| Risk Codes | R20/21/22 - Harmful by inhalation, in contact with skin and if swallowed. R34 - Causes burns |
| Safety Description | S16 - Keep away from sources of ignition. S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. S27 - Take off immediately all contaminated clothing. S36/37/39 - Wear suitable protective clothing, gloves and eye/face protection. S45 - In case of accident or if you feel unwell, seek medical advice immediately (show the label whenever possible.) |
| UN IDs | UN 2619 8/PG 2 |
| WGK Germany | 3 |
| Hazard Class | 8 |
| Packing Group | III |
(S)-(-)-4-(1-AMINOETHYL)TOLUENE - Introduction
(S)-1-(4-Methylphenyl)ethylamine, chemical name (S)-1-(4-Methylphenyl)ethylamine, is a chiral compound, usually liquid or solid. The following is a description of the properties, uses, preparation and safety information of the compound:
Nature:
-Appearance: usually colorless or yellowish transparent liquid, may also be solid or crystalline.
-Molecular formula: C9H13N
-relative molecular mass: 135.21g/mol
-Melting Point: 54-55 ℃
-Boiling Point: 196-197 ℃
-optical rotation:[α]D 25=-16.5 ° (c = 1, CHCl3)
-Solubility: Soluble in general organic solvents, such as ethanol, acetone and dichloromethane.
Use:
- (S)-1-(4-Methylphenyl)ethylamine is a chiral amine compound, which is often used as a separation reagent and an important raw material in Chiral synthesis.
-It can also be used as a catalyst to participate in organic synthesis reactions and has important application value.
Method:
There are many ways to synthesize (S)-1-(4-Methylphenyl)ethylamine, and the common ones are as follows:
1. According to the principle of Chiral synthesis, the target compound can be synthesized by chiral resolution.
2. The target compound is prepared by reacting a synthetic precursor having a chiral center with a chiral conversion reagent.
3. Relying on chiral catalysts to promote asymmetric reactions to generate target compounds.
Safety Information:
-Due to the toxicity of the compound, appropriate laboratory safety precautions should be taken, gloves and goggles should be worn, and the operation should be carried out in a well-ventilated laboratory.
-Avoid contact with skin and eyes. If contact occurs, rinse immediately with plenty of water.
-Avoid inhaling vapors of compounds. If inhaled, Please quickly get out of the contaminated area and seek medical help.
-The compound should be stored in a cool and dry place, and away from fire and flammable substances.
-Do not mix this compound with a strong oxidant to avoid dangerous reactions.
Nature:
-Appearance: usually colorless or yellowish transparent liquid, may also be solid or crystalline.
-Molecular formula: C9H13N
-relative molecular mass: 135.21g/mol
-Melting Point: 54-55 ℃
-Boiling Point: 196-197 ℃
-optical rotation:[α]D 25=-16.5 ° (c = 1, CHCl3)
-Solubility: Soluble in general organic solvents, such as ethanol, acetone and dichloromethane.
Use:
- (S)-1-(4-Methylphenyl)ethylamine is a chiral amine compound, which is often used as a separation reagent and an important raw material in Chiral synthesis.
-It can also be used as a catalyst to participate in organic synthesis reactions and has important application value.
Method:
There are many ways to synthesize (S)-1-(4-Methylphenyl)ethylamine, and the common ones are as follows:
1. According to the principle of Chiral synthesis, the target compound can be synthesized by chiral resolution.
2. The target compound is prepared by reacting a synthetic precursor having a chiral center with a chiral conversion reagent.
3. Relying on chiral catalysts to promote asymmetric reactions to generate target compounds.
Safety Information:
-Due to the toxicity of the compound, appropriate laboratory safety precautions should be taken, gloves and goggles should be worn, and the operation should be carried out in a well-ventilated laboratory.
-Avoid contact with skin and eyes. If contact occurs, rinse immediately with plenty of water.
-Avoid inhaling vapors of compounds. If inhaled, Please quickly get out of the contaminated area and seek medical help.
-The compound should be stored in a cool and dry place, and away from fire and flammable substances.
-Do not mix this compound with a strong oxidant to avoid dangerous reactions.
Last Update：2024-04-10 22:29:15
