(S)-(3-(Aminomethyl)-1,2,4-oxadiazol-5-yl)(3-hydroxypyrrolidin-1-yl)methanone
(3S)-1-{[3-(Aminomethyl)-1,2,4-oxadiazol-5-yl]-carbonyl}pyrrolidin-3-ol
CAS: 1186662-39-4
Molecular Formula: C8H12N4O3
(S)-(3-(Aminomethyl)-1,2,4-oxadiazol-5-yl)(3-hydroxypyrrolidin-1-yl)methanone - Names and Identifiers
(S)-(3-(Aminomethyl)-1,2,4-oxadiazol-5-yl)(3-hydroxypyrrolidin-1-yl)methanone - Physico-chemical Properties
| Molecular Formula | C8H12N4O3 |
| Molar Mass | 212.21 |
| Storage Condition | Room Temprature |
| Sensitive | Irritant |
| MDL | MFCD12026798 |
(S)-(3-(Aminomethyl)-1,2,4-oxadiazol-5-yl)(3-hydroxypyrrolidin-1-yl)methanone - Introduction
(3S)-1-{[3-(Aminomethyl)-1,2,4-oxadiazol-5-yl]-carbonyl}pyrrolidin-3-ol is an organic compound, which may also be abbreviated as AMOX. Its molecular formula is C7H10N4O3 and its molecular weight is 198.18g/mol.
The following is a detailed description of the nature, use, manufacture and safety information of AMOX:
Nature:
AMOX is a solid powder with a white or off-white appearance. It is relatively stable at room temperature and has good solubility. Its pKa value is 7.63.
Use:
AMOX has many applications, one of which is as an amine protector in organic synthesis. It can make the synthesis process more controllable and efficient by protecting the amine group from undesirable reactions.
Preparation Method:
The preparation of AMOX can be carried out by the following steps:
1. Take dimethylhydrazine oxide and glycine for condensation reaction to obtain (N-boc-amino-methyl)glycine.
2. react (N-boc-amino-methyl)glycine with excess methyl nitrite to generate methyl nitrite salt.
3. Methyl nitrite salt reacts with HCl to produce nitrite.
4. this nitrite is synthesized into N'-cyano-N-nitroso-N-methylthiourea intermediate by reaction and acetylene ketone condensation.
5. The intermediate generates AMOX by reaction.
Safety Information:
AMOX is relatively safe under the conditions of correct use and storage, but the following points still need to be paid attention:
1. AMOX may be irritating to the eyes, skin and respiratory system. After contact, rinse with plenty of water immediately. If you have persistent discomfort, seek medical help.
2. Avoid inhaling AMOX powder or gases, operate in a well-ventilated place, and wear appropriate protective equipment, such as protective glasses, gloves and masks.
3. AMOX should be stored in a dry, ventilated place, away from fire and oxidant. Avoid contact with flammable substances.
4. During use, the operation should be carried out in strict accordance with the safety operation procedures and abide by the local laws and regulations.
Please note that for the handling and use of chemical substances, it is recommended to carry out under the guidance of professionals, and check and understand relevant safety information before operation.
The following is a detailed description of the nature, use, manufacture and safety information of AMOX:
Nature:
AMOX is a solid powder with a white or off-white appearance. It is relatively stable at room temperature and has good solubility. Its pKa value is 7.63.
Use:
AMOX has many applications, one of which is as an amine protector in organic synthesis. It can make the synthesis process more controllable and efficient by protecting the amine group from undesirable reactions.
Preparation Method:
The preparation of AMOX can be carried out by the following steps:
1. Take dimethylhydrazine oxide and glycine for condensation reaction to obtain (N-boc-amino-methyl)glycine.
2. react (N-boc-amino-methyl)glycine with excess methyl nitrite to generate methyl nitrite salt.
3. Methyl nitrite salt reacts with HCl to produce nitrite.
4. this nitrite is synthesized into N'-cyano-N-nitroso-N-methylthiourea intermediate by reaction and acetylene ketone condensation.
5. The intermediate generates AMOX by reaction.
Safety Information:
AMOX is relatively safe under the conditions of correct use and storage, but the following points still need to be paid attention:
1. AMOX may be irritating to the eyes, skin and respiratory system. After contact, rinse with plenty of water immediately. If you have persistent discomfort, seek medical help.
2. Avoid inhaling AMOX powder or gases, operate in a well-ventilated place, and wear appropriate protective equipment, such as protective glasses, gloves and masks.
3. AMOX should be stored in a dry, ventilated place, away from fire and oxidant. Avoid contact with flammable substances.
4. During use, the operation should be carried out in strict accordance with the safety operation procedures and abide by the local laws and regulations.
Please note that for the handling and use of chemical substances, it is recommended to carry out under the guidance of professionals, and check and understand relevant safety information before operation.
Last Update：2024-04-10 22:29:15
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