(S)-1-(2-Chloroacetyl)pyrrolidine-2-carboxaMide
2-Pyrrolidinecarboxamide,1-(2-chloroacetyl)-, (2S)-
CAS: 214398-99-9
Molecular Formula: C7H11ClN2O2
(S)-1-(2-Chloroacetyl)pyrrolidine-2-carboxaMide - Names and Identifiers
(S)-1-(2-Chloroacetyl)pyrrolidine-2-carboxaMide - Physico-chemical Properties
| Molecular Formula | C7H11ClN2O2 |
| Molar Mass | 190.63 |
| Density | 1.353±0.06 g/cm3(Predicted) |
| Melting Point | 133-137℃ (isopropyl ether ) |
| Boling Point | 442.5±45.0 °C(Predicted) |
| Solubility | Chloroform (Slightly, Sonicated), DMSO (Slightly), Methanol (Very Slightly) |
| Appearance | Solid |
| Color | White to Pale Beige |
| pKa | 15.56±0.20(Predicted) |
| Storage Condition | under inert gas (nitrogen or Argon) at 2-8°C |
| Sensitive | Irritant |
| MDL | MFCD11845729 |
(S)-1-(2-Chloroacetyl)pyrrolidine-2-carboxaMide - Introduction
2-Pyrrolidinecarboxamide,1-(2-choroacetyl)-, (2S)-, also known as (2-Pyrrolidinecarboxamide,1-(2-choroacetyl)-, (2S)-, is an organic compound. The following is a description of the properties, uses, preparation and safety information of the compound:
Nature:
-chemical formula: C8H12ClNO
-Molecular weight: 171.64g/mol
-Appearance: Usually white or off-white solid
-Melting Point: 80-84 ℃
-Boiling point: 341.7 ℃
-Solubility: Poor solubility in water, soluble in some organic solvents such as dichloromethane and methanol
Use:
-2-yrrolidinecarboxamide, 1-(2-chrooacetyl)-, (2S)-is often used as an important intermediate compound in organic synthesis for the synthesis of drugs, pesticides and other biologically active compounds.
-It can also be used as a reagent for pharmaceutical research. By modifying its structure, derivatives with different biological activities can be produced.
Method:
The preparation of-2-Pyrrolidinecarboxamide,1-(2-chloroacetyl)-, (2S)-can be obtained by reacting pyrrolidine amide with chloroacetic acid chloride. The reaction conditions are such that the reactants are added in an organic solvent at room temperature, and after stirring the reaction for a period of time, the target product is obtained by crystallization, filtration and drying.
Safety Information:
-2-yrrolidinecarboxamide, 1-(2-chrooacetyl)-, (2S)-Care should be taken to prevent inhalation, skin contact and ingestion during use. Wear appropriate protective equipment such as gloves, glasses and masks when used.
-In case of exposure to the compound, rinse contaminated skin immediately with plenty of water and seek medical advice.
-During storage, it should be stored in a dry and cool place, and stored separately from oxidants, acids, alkalis and other substances.
Nature:
-chemical formula: C8H12ClNO
-Molecular weight: 171.64g/mol
-Appearance: Usually white or off-white solid
-Melting Point: 80-84 ℃
-Boiling point: 341.7 ℃
-Solubility: Poor solubility in water, soluble in some organic solvents such as dichloromethane and methanol
Use:
-2-yrrolidinecarboxamide, 1-(2-chrooacetyl)-, (2S)-is often used as an important intermediate compound in organic synthesis for the synthesis of drugs, pesticides and other biologically active compounds.
-It can also be used as a reagent for pharmaceutical research. By modifying its structure, derivatives with different biological activities can be produced.
Method:
The preparation of-2-Pyrrolidinecarboxamide,1-(2-chloroacetyl)-, (2S)-can be obtained by reacting pyrrolidine amide with chloroacetic acid chloride. The reaction conditions are such that the reactants are added in an organic solvent at room temperature, and after stirring the reaction for a period of time, the target product is obtained by crystallization, filtration and drying.
Safety Information:
-2-yrrolidinecarboxamide, 1-(2-chrooacetyl)-, (2S)-Care should be taken to prevent inhalation, skin contact and ingestion during use. Wear appropriate protective equipment such as gloves, glasses and masks when used.
-In case of exposure to the compound, rinse contaminated skin immediately with plenty of water and seek medical advice.
-During storage, it should be stored in a dry and cool place, and stored separately from oxidants, acids, alkalis and other substances.
Last Update：2024-04-09 15:17:55
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CAS: 214398-99-9
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