(S)-1-aminoindane
(S)-1-aminoindane
CAS: 61341-86-4
Molecular Formula: C9H11N
(S)-1-aminoindane - Names and Identifiers
(S)-1-aminoindane - Physico-chemical Properties
| Molecular Formula | C9H11N |
| Molar Mass | 133.19 |
| Density | 1.038g/mLat 25°C(lit.) |
| Melting Point | 15 °C |
| Boling Point | 96-97°C8mm Hg(lit.) |
| Specific Rotation(α) | 20 º (c=1.5, CH3OH) |
| Flash Point | 202°F |
| Water Solubility | insoluble |
| Appearance | Liquid |
| Color | Clear yellow |
| BRN | 2206708 |
| pKa | 9.44±0.20(Predicted) |
| Storage Condition | Keep in dark place,Sealed in dry,2-8°C |
| Sensitive | Air Sensitive |
| Refractive Index | n20/D 1.562(lit.) |
(S)-1-aminoindane - Risk and Safety
| Hazard Symbols | Xi - Irritant |
| Risk Codes | R36/37/38 - Irritating to eyes, respiratory system and skin. R52/53 - Harmful to aquatic organisms, may cause long-term adverse effects in the aquatic environment. |
| Safety Description | S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. S36 - Wear suitable protective clothing. S37/39 - Wear suitable gloves and eye/face protection S61 - Avoid release to the environment. Refer to special instructions / safety data sheets. |
| UN IDs | UN 3082 9 / PGIII |
| WGK Germany | 3 |
| FLUKA BRAND F CODES | 10-34 |
| HS Code | 29214990 |
(S)-1-aminoindane - Reference Information
| application | (S)-1-amino indene is full of an important pharmaceutical intermediate, mainly used in the synthesis of chiral drugs such as rasagline. |
| preparation | add 1.00g(4.80 mmol) di-(s-(+) -1-amino indan)-d-tartrate into a 250 mL flask, 40 mL water, stir and heat to completely dissolve it, cool to room temperature, add 20% NaOH solution dropwise, and adjust PH to 10, each time with 40 mL trichloromethane extraction, extraction three times, combined organic phase, with anhydrous magnesium sulfate drying for 20 min, filtration, concentration, 0.97g light yellow liquid (S)-(+) -1-amino indan, ee value (HPLC method) is 79.6%, the yield is 97.0%. |
Last Update：2024-04-10 22:30:50
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CAS: 61341-86-4
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CAS: 61341-86-4
Tel: 0714-3999186
Email: 2853786052@qq.com
Mobile: 86+15671228036
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