(S)-2,2-Dimethyl-3-(N-Boc)-4-ethynyl-oxazolidine

(S)-2,2-Dimethyl-3-(N-Boc)-4-ethynyl-oxazolidine - Names and Identifiers

Name	(S)-2,2-Dimethyl-3-(N-Boc)-4-ethynyl-oxazolidine
Synonyms	(S)-2,2-DIMETHYL-3-BOC-4-ETHYNYLOXAZOLIDINE (S)-2,2-Dimethyl-3-(N-Boc)-4-ethynyl-oxazolidine tert-Butyl (S)-4-ethynyl-2,2-dimethyloxazolidine-3-carboxylate (S)-TERT-BUTYL 4-ETHYNYL-2,2-DIMETHYLOXAZOLIDINE-3-CARBOXYLATE tert-Butyl (4S)-4-ethynyl-2,2-dimethyl-1,3-oxazolidine-3-carboxylate tert-Butyl (4s)-4-ethynyl-2,2-dimethyl-1,3-oxazolidine-3-carboxylate (4S)-4-Ethynyl-2,2-dimethyl-3-oxazolidinecarboxylic acid 1,1-dimethylethyl ester
CAS	173065-16-2

(S)-2,2-Dimethyl-3-(N-Boc)-4-ethynyl-oxazolidine - Physico-chemical Properties

Molecular Formula	C12H19NO3
Molar Mass	225.28
Density	1.06
Boling Point	277℃
Flash Point	121℃
Storage Condition	2-8°C

(S)-2,2-Dimethyl-3-(N-Boc)-4-ethynyl-oxazolidine - Introduction

(S)-2,2-dimethyl-3-(N-Boc)-4-ethynyl-oxazolidine is an organic compound with the following properties:

1. Appearance: a colorless liquid.
2. Molecular formula: C11H18N2O2.
3. Molecular weight: 214.27g/mol.
4. Melting point:-35 ° C.
5. Boiling Point: 162-165 C.
6. Solubility: Soluble in some organic solvents, such as ether and alcohol.

This substance has the following uses:

1. As a chemical reagent: can be used as a catalyst and reagent in organic synthesis.
2. As a solvent: Due to its good solubility, it can be used as a solvent for organic synthesis reactions.

The preparation of (S)-2,2-dimethyl-3-(N-Boc)-4-ethynyl-oxazolidine can be carried out by the following steps:

1. First, the formic acid and bromoacetylene reaction, generate bromoacetylene acid.
2. Then, bromoacetylene acid and N-tert-butyl oxazolidine are reacted to generate (S)-2,2-dimethyl-3-(N-Boc)-4-ethynyl-oxazolidine.

Regarding its safety information, the following matters need to be noted:

1. It is a flammable liquid and should avoid exposure to open flames and high temperatures.
2. In use or storage, must be away from the fire and oxygen.
3. When using, should wear appropriate protective equipment, such as gloves and goggles.
4. Avoid contact with skin, eyes and mucous membranes, such as accidental contact, should immediately rinse with plenty of water.
5. Storage, should be sealed in a cool, dry place.
6. If ingested or inhaled, seek medical attention immediately.

Last Update：2024-04-10 22:29:15