(S)-2-AMino-2-(3-fluorophenyl)ethanol

(S)-2-AMino-2-(3-fluorophenyl)ethanol - Names and Identifiers

Name	(2S)-2-Amino-2-(3-fluorophenyl)ethanol
Synonyms	(S)-2-AMino-2-(3-fluorophenyl)ethanol (2S)-2-Amino-2-(3-fluorophenyl)ethanol (2S)-2-amino-2-(3-fluorophenyl)ethanol (S)-2-amino-2-(3-fluorophenyl)ethan-1-ol Benzeneethanol, β-amino-3-fluoro-, (βS)- (2S)-2-AMino-2-(3-fluorophenyl)ethan-1-ol Benzeneethanol, beta-amino-3-fluoro-, (betas)- Benzeneethanol, beta-amino-3-fluoro-, (betaS)- (9CI)
CAS	325152-98-5
InChI	InChI=1S/C8H10FNO/c9-7-3-1-2-6(4-7)8(10)5-11/h1-4,8,11H,5,10H2/t8-/m1/s1

(S)-2-AMino-2-(3-fluorophenyl)ethanol - Physico-chemical Properties

Molecular Formula	C8H10FNO
Molar Mass	155.17
Density	1.208±0.06 g/cm3(Predicted)
Melting Point	101-103 °C
Boling Point	286.3±25.0 °C(Predicted)
pKa	12.40±0.10(Predicted)
Storage Condition	under inert gas (nitrogen or Argon) at 2–8 °C

(S)-2-AMino-2-(3-fluorophenyl)ethanol - Introduction

(2S)-2-Amino-2-(3-fluorophenyl)ethanol is a chiral organic compound with the chemical structure of C8H10FNO. The following are some of the properties, uses, preparation and safety information of the compound:

Nature:
-Appearance: Colorless to light yellow solid
-Melting point: About 85-90 ℃
-Boiling point: About 312 ℃
-Solubility: Limited solubility in water, soluble in many organic solvents such as ethanol and dimethylformamide
-optical rotation:(2S)-2-Amino-2-(3-fluorophenyl)ethanol shows L-optical activity

Use:
(2S)-2-Amino-2-(3-fluorophenyl)ethanol is often used as a chiral intermediate in organic synthesis. It can be used in drug synthesis, Pesticide Synthesis, spice synthesis and other fields, and has a wide range of applications.

Method:
(2S)-2-Amino-2-(3-fluorophenyl)ethanol can be prepared by the following steps:
1.2-(3-fluorophenyl) acetonitrile was obtained by cyanidation synthesis
2. React 2-(3-fluorophenyl) acetonitrile with an appropriate amount of ammonia water to generate (2S)-2-Amino-2-(3-fluorophenyl)ethanol

Safety Information:
Under the correct use and storage conditions, the compound is usually less harmful to the human body and the environment. However, caution should be exercised with any chemical substance and safe handling guidelines should be followed. When conducting experiments or industrial production, appropriate protective measures should be taken, such as wearing protective glasses, masks and gloves. For human contact, rinse immediately with soap and water. If necessary, follow the relevant emergency procedures and consult a professional or doctor.

Last Update：2024-04-09 20:45:29