(S)-2-benzyl-N,N-dimethylaziridine-1-solfonamide

Name	(S)-2-Benzyl-N,N-dimethylaziridine-1-sulfonamide
Synonyms	-2-Benzyl-N,N-dimethylaziridine-1-sulfonamide (S)-2-benzyl-N,N-dimethylaziridine-1-solfonamide (S)-2-Benzyl-N,N-dimethylaziridine-1-sulfonamide N,N-Dimethyl-2-benzyl-(2S)-1-aziridinesulfonamide (2S)-2-benzyl-N,N-dimethylaziridine-1-sulfonamide N,N-Dimethyl-2-Benzyl-(2S)-1-Aziridinesulfonamide (S)-2-benzyl-N,N-dimethylaziridine-1-solfonamide (BDS) 1-Aziridinesulfonamide, N,N-dimethyl-2-(phenylmethyl)-, (2S)-
CAS	902146-43-4
EINECS	620-285-0
InChI	InChI=1S/C11H16N2O2S/c1-12(2)16(14,15)13-9-11(13)8-10-6-4-3-5-7-10/h3-7,11H,8-9H2,1-2H3/t11-,13?/m0/s1

Use	(S)-2-benzyl-N,N-dimethylazetidinyl-1-sulfonamide is a reagent for the synthesis of N-alkylsulfamic acid derivatives. It may also be used in the preparation of pharmaceutical peptide analogs.
apply	(S)-2-benzyl-N,N-dimethylazetidinyl-1-sulfonamide is an intermediate for the preparation of Selegiline. Selegi is a highly efficient, highly selective, irreversible monoamine oxidase B(MAO-B) inhibitor, can enhance the transmission of dopamine signal, blocking brain dopamine decomposition, delay or reduce the death of dopamine cells in the substantia nigra of the brain, and its hydrochloride is clinically used for the treatment of Parkinson's disease, Alzheimer's disease and depression.
preparation method	(S)-2-benzyl-N, the procedure for the preparation of N-dimethylaziridinyl -1-sulfonamide is as follows: Step 1: compound (S)-2-amino -3-phenyl propan-1-ol preparation Step 2: compound (S)-2-benzyl cycloethyleneimine preparation Step 3: compound (S) preparation of-2-benzyl-n, n-dimethylazirido-1-sulfonamide

Last Update：2024-04-10 22:29:15