(S)-ALPHA-METHYL-4-CARBOXYPHENYLGLYCINE
(+)-Alpha-Methyl-4-Carboxyphenylglycine
CAS: 150145-89-4
Molecular Formula: C10H11NO4
(S)-ALPHA-METHYL-4-CARBOXYPHENYLGLYCINE - Names and Identifiers
(S)-ALPHA-METHYL-4-CARBOXYPHENYLGLYCINE - Physico-chemical Properties
| Molecular Formula | C10H11NO4 |
| Molar Mass | 209.2 |
| Solubility | 0.1 M NaOH: 15mg/mL |
| Appearance | solid |
| Color | White to off-white |
| Storage Condition | Store at RT |
| In vitro study | (S)-MCPG (100 μM) has no detectable effects on basal spine formation or elimination mechanisms in WT slice cultures. (S)-MCPG prevents the increase in spine turnover triggered by TBS and interferes with the mechanisms of activity-dependent spine stabilization in Hippocampal slice cultures. |
(S)-ALPHA-METHYL-4-CARBOXYPHENYLGLYCINE - Risk and Safety
| Safety Description | 24/25 - Avoid contact with skin and eyes. |
| WGK Germany | 3 |
| HS Code | 29224985 |
(S)-ALPHA-METHYL-4-CARBOXYPHENYLGLYCINE - Preparation solution concentration reference
| 1mg | 5mg | 10mg | |
|---|---|---|---|
| 1 mM | 4.78 ml | 23.901 ml | 47.801 ml |
| 5 mM | 0.956 ml | 4.78 ml | 9.56 ml |
| 10 mM | 0.478 ml | 2.39 ml | 4.78 ml |
| 5 mM | 0.096 ml | 0.478 ml | 0.956 ml |
Last Update：2024-01-02 23:10:35
(S)-ALPHA-METHYL-4-CARBOXYPHENYLGLYCINE - Reference Information
| biological activity | (S)-MCPG (( )-MCPG) it is a potent class I/II metabotropic glutamate receptor (mGluRs) antagonist and is the active isomer of (RS)-MCPG (HY-100371). (S)-MCPG can be used to study the role of mGluRs in spatial learning. |
| Animal Model: | Male Lister-Hooded rats in the learning of the Morris water maze |
| Dosage: | 20 μg |
| Administration: | Intraventricular injection; 20 μg; 4 days |
| Result: | Impaired the performance of rats in the spatial version of the Morris water maze, but 1/10 of this dose did not. |
Last Update：2024-04-09 20:52:54
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View History
(S)-ALPHA-METHYL-4-CARBOXYPHENYLGLYCINE
3-苯基-2-硫代乙内酰脲-5-丙酰胺
CRYPTOFIX 222
H-D-Val-OMe•HCl
2-NITRO-4-PICOLINE
3-甲基-1-丙基-1h-吡唑-4-磺酰氯
1-CHLORO-3-PHENYLACETONE
2-(3-PYRIDYL) PIPERIDINE HYDROCHLORIDE
2 3 4 5 -四甲基-2-环戊烯酮
甲基环己烯-1,2-二甲酸酐 (异构体混合物)
3-苯基-2-硫代乙内酰脲-5-丙酰胺
CRYPTOFIX 222
H-D-Val-OMe•HCl
2-NITRO-4-PICOLINE
3-甲基-1-丙基-1h-吡唑-4-磺酰氯
1-CHLORO-3-PHENYLACETONE
2-(3-PYRIDYL) PIPERIDINE HYDROCHLORIDE
2 3 4 5 -四甲基-2-环戊烯酮
甲基环己烯-1,2-二甲酸酐 (异构体混合物)