(S)-Benzyl-3-Aminopyrrolidine-1-Carboxylate
(S)-3-Amino-1-Cbz-Pyrrolidine
CAS: 122536-72-5
Molecular Formula: C12H16N2O2
(S)-Benzyl-3-Aminopyrrolidine-1-Carboxylate - Names and Identifiers
| Name | (S)-3-Amino-1-Cbz-Pyrrolidine |
| Synonyms | (S)-3-AMINO-1-CBZ-PYRROLIDINE (S)-3-Amino-1-Cbz-Pyrrolidine (S)-3-Amino-1-N-Cbz-pyrrolidine (S)-(+)-1-CBZ-3-AMINOPYRROLIDINE (S)-(+)-1-Cbz-3-Aminopyrrolidine (S)-3-AMino-1-N-cbz-pyrrolidine HCl (S)-1-BENZYLOXYCARBONYL-3-AMINOPYRROLIDINE (S)-1-Benzyloxycarbonyl-3-Aminopyrrolidine (S)-BENZYL-3-AMINOPYRROLIDINE-1-CARBOXYLATE (S)-Benzyl-3-Aminopyrrolidine-1-Carboxylate benzyl (3S)-3-aminopyrrolidine-1-carboxylate |
| CAS | 122536-72-5 |
| InChI | InChI=1/C12H16N2O2/c13-11-6-7-14(8-11)12(15)16-9-10-4-2-1-3-5-10/h1-5,11H,6-9,13H2/t11-/m0/s1 |
(S)-Benzyl-3-Aminopyrrolidine-1-Carboxylate - Physico-chemical Properties
| Molecular Formula | C12H16N2O2 |
| Molar Mass | 220.27 |
| Density | 1.155g/mLat 25°C |
| Melting Point | 310-316℃ |
| Boling Point | 315°C |
| Flash Point | >230°F |
| Vapor Presure | 4.04E-05mmHg at 25°C |
| pKa | 9.52±0.20(Predicted) |
| Sensitive | Air Sensitive |
| Refractive Index | n20/D 1.548 |
| Physical and Chemical Properties | WGK Germany:3 |
(S)-Benzyl-3-Aminopyrrolidine-1-Carboxylate - Risk and Safety
| Hazard Symbols | Xn - Harmful |
| Risk Codes | R22 - Harmful if swallowed R36/37/38 - Irritating to eyes, respiratory system and skin. |
| Safety Description | S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. S36 - Wear suitable protective clothing. |
| WGK Germany | 3 |
| HS Code | 29339900 |
(S)-Benzyl-3-Aminopyrrolidine-1-Carboxylate - Introduction
(S)-1-Benzyloxycarbonyl-3-aminopyrrolidine, also known as benzyloxycarbonyl-N-propyl-3-aminopyrrolidine, is an organic compound. Its chemical formula is C11H15N3O2.
Properties of the compound:
-Appearance: A colorless to light yellow crystal.
-Solubility: Soluble in common organic solvents such as ethanol and chloroform, insoluble in water.
-Melting point: about 120-123°C.
Main uses of the compound:
-Biological research: As an ion channel modulator, it is used to study and regulate neurotransmission and intracellular signal transmission mechanisms.
-Drug research and development: As a protective group of polypeptides and proteins in the application of drug synthesis, play a protective role.
Preparation of the compound:
The preparation of (S)-1-benzyloxycarbonyl-3-aminopyrrolidine is usually obtained by a chiral resolution method of benzyloxycarbonyl-N-propyl-3-aminopyrrolidine. Resolution methods typically involve chirally related amino acid synthesis and preparation of chiral complexes.
Safety information for this compound:
-Allergenicity: This compound may be allergenic and should be noted by contact allergy sufferers.
-Toxicity: The toxicity of this compound has not been fully studied so far, and it must be used in accordance with laboratory safety procedures.
-Flammability: The compound is flammable and should be kept away from open flames and heat sources.
-Storage: It should be stored in a sealed, dark, dry and well-ventilated place.
-Waste disposal: Dispose of waste in accordance with local laws and regulations to avoid environmental pollution.
Properties of the compound:
-Appearance: A colorless to light yellow crystal.
-Solubility: Soluble in common organic solvents such as ethanol and chloroform, insoluble in water.
-Melting point: about 120-123°C.
Main uses of the compound:
-Biological research: As an ion channel modulator, it is used to study and regulate neurotransmission and intracellular signal transmission mechanisms.
-Drug research and development: As a protective group of polypeptides and proteins in the application of drug synthesis, play a protective role.
Preparation of the compound:
The preparation of (S)-1-benzyloxycarbonyl-3-aminopyrrolidine is usually obtained by a chiral resolution method of benzyloxycarbonyl-N-propyl-3-aminopyrrolidine. Resolution methods typically involve chirally related amino acid synthesis and preparation of chiral complexes.
Safety information for this compound:
-Allergenicity: This compound may be allergenic and should be noted by contact allergy sufferers.
-Toxicity: The toxicity of this compound has not been fully studied so far, and it must be used in accordance with laboratory safety procedures.
-Flammability: The compound is flammable and should be kept away from open flames and heat sources.
-Storage: It should be stored in a sealed, dark, dry and well-ventilated place.
-Waste disposal: Dispose of waste in accordance with local laws and regulations to avoid environmental pollution.
Last Update：2024-04-09 02:00:41
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