(S)-Hydroxyphenylacetonitrile

(S)-Hydroxyphenylacetonitrile - Names and Identifiers

Name	S-(-)-Mandelonitrile
Synonyms	(S)-Mandelonitrile S-(-)-Mandelonitrile (-)-L-Mandelonitrile (S)-Hydroxyphenylacetonitrile (S)-Phenyl(hydroxy)acetonitrile (S)-2-Hydroxy-2-phenylacetonitrile (S)-2-Phenyl-2-hydroxyacetonitrile [S,(-)]-α-Hydroxybenzeneacetonitrile Benzeneacetonitrile, α-hydroxy-, (αS)-
CAS	28549-12-4

(S)-Hydroxyphenylacetonitrile - Physico-chemical Properties

Molecular Formula	C8H7NO
Molar Mass	133.15
Density	1.169±0.06 g/cm3(Predicted)
Boling Point	282.7±20.0 °C(Predicted)
pKa	10.50±0.20(Predicted)
Storage Condition	Keep in dark place,Inert atmosphere,Store in freezer, under -20°C

(S)-Hydroxyphenylacetonitrile - Introduction

S-(-)-Mandelonitrile, also known as S-(-)-Mandelonitrile, is an organic compound. The following is a description of the properties, uses, preparation and safety information of the compound:

Nature:
S-(-)-Mandelonitrile is a colorless liquid with a bitter almond flavor. Its chemical formula is C8H7NO and its molecular weight is 133.15g/mol. The compound has a boiling point of 162-163°C and a density of 1.042g/cm³. S-(-)-mandelonium is soluble in water and ethanol, and is easily hydrolyzed under alkaline conditions.

Use:
S-(-)-Mandelonitrile has a wide range of applications in the field of chemical synthesis. It is an important intermediate for the synthesis of chiral drugs and pesticides. In addition, it is also used as a catalyst and solvent, and can be used for the action of amines in organic synthesis reactions.

Method:
The preparation of S-(-)-Mandelonitrile is usually obtained by reaction using sodium cyanide in the presence of benzaldehyde. The reaction conditions may be carried out at low temperature and using an organic solvent as the reaction medium.

Safety Information:
S-(-)-Mandelonitrile is a toxic compound that may have irritating and damaging effects on the human body. Contact with the skin and inhalation of its vapors may cause irritation, burning and allergic reactions. Therefore, appropriate protective equipment such as gloves, goggles and face shields should be worn during use to avoid direct contact. In addition, it should be operated in a well-ventilated place to avoid inhalation of vapors. During storage, the S-(-)-Mandelonitrile should be stored in a dry, cool, ventilated place, away from fire and oxidizing agents. In case of accidents, appropriate emergency measures shall be taken immediately and medical treatment shall be taken in time.

Last Update：2024-04-09 20:52:54