(S)-N-Boc-3-aminomethylpiperidine
(S)-N-Boc-3-aminomethylpiperidine
CAS: 140645-24-5
Molecular Formula: C11H22N2O2
(S)-N-Boc-3-aminomethylpiperidine - Names and Identifiers
(S)-N-Boc-3-aminomethylpiperidine - Physico-chemical Properties
| Molecular Formula | C11H22N2O2 |
| Molar Mass | 214.3 |
| Density | 1.008 g/mL at 25 °C |
| Boling Point | 299.4±13.0 °C(Predicted) |
| Flash Point | >110 °C |
| Vapor Presure | 0.00119mmHg at 25°C |
| Appearance | Liquid |
| Color | Clear colorless |
| pKa | 10.12±0.29(Predicted) |
| Storage Condition | 2-8°C |
| Refractive Index | n20/D 1.4754 |
(S)-N-Boc-3-aminomethylpiperidine - Risk and Safety
| Risk Codes | R22 - Harmful if swallowed R50 - Very Toxic to aquatic organisms R36/37/38 - Irritating to eyes, respiratory system and skin. |
| Safety Description | S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. S61 - Avoid release to the environment. Refer to special instructions / safety data sheets. S37 - Wear suitable gloves. |
| UN IDs | UN 3082 9 / PGIII |
| WGK Germany | 2 |
| HS Code | 29333990 |
(S)-N-Boc-3-aminomethylpiperidine - Introduction
(S)-1-Boc-3-aminomethylpiperidine is an organic compound with the chemical structure: Boc-NH-CH2-C6H4-CH2-NH-C3H6.
It is a white crystalline solid, stable at room temperature. It is a compound with amino and hydrocarbon groups, with moderate to weak alkalinity. The Boc group in the molecule is tert-butoxycarbonyl, which can enhance the solubility of the compound and protect the amino group to prevent the reaction.
The main use of this compound is as an intermediate in organic synthesis. It can be used to synthesize other compounds, such as drugs, pesticides, pigments and dyes. It is particularly commonly used in drug synthesis and can be used to prepare compounds containing piperidine structures, such as antiviral drugs, anticancer drugs, etc.
A common method for preparing (S)-1-Boc-3-aminomethylpiperidine is to react piperidine with methyl chloride to obtain the methyl derivative of piperidine, which is then reacted with tert-butoxycarbonyl chloride to produce the target product.
Regarding its safety information, it is a chemical that needs to be handled and stored correctly to ensure the safety of the workplace. It may be irritating to the eyes and skin, so you need to pay attention to avoid direct contact during use. It is also important to follow proper laboratory procedures and use appropriate personal protective equipment.
It is a white crystalline solid, stable at room temperature. It is a compound with amino and hydrocarbon groups, with moderate to weak alkalinity. The Boc group in the molecule is tert-butoxycarbonyl, which can enhance the solubility of the compound and protect the amino group to prevent the reaction.
The main use of this compound is as an intermediate in organic synthesis. It can be used to synthesize other compounds, such as drugs, pesticides, pigments and dyes. It is particularly commonly used in drug synthesis and can be used to prepare compounds containing piperidine structures, such as antiviral drugs, anticancer drugs, etc.
A common method for preparing (S)-1-Boc-3-aminomethylpiperidine is to react piperidine with methyl chloride to obtain the methyl derivative of piperidine, which is then reacted with tert-butoxycarbonyl chloride to produce the target product.
Regarding its safety information, it is a chemical that needs to be handled and stored correctly to ensure the safety of the workplace. It may be irritating to the eyes and skin, so you need to pay attention to avoid direct contact during use. It is also important to follow proper laboratory procedures and use appropriate personal protective equipment.
Last Update：2024-04-09 21:54:55
