(S)-NA-CBZ-2-BOCAMINOMETHYLGLYCINE - Names and Identifiers
Name | Z-Dap(Boc)-OH
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Synonyms | Z-Dap(Boc)-OH CBZ-L-DAP(BOC)-OH RARECHEM EM WB 0114 L-N-Cbz-3-N-Boc-Amino-Alanine L-N-CBZ-3-N-BOC-AMINO-ALANINE (S)-NA-CBZ-2-BOCAMINOMETHYLGLYCINE Z-L-Dap(BOC)-O Cbz-N3-Boc- L-2,3-diaMinopropionic acid N-[(benzyloxy)carbonyl]-3-[(tert-butoxycarbonyl)amino]-L-alanine (S)-2-BENZYLOXYCARBONYLAMINO-3-TERT-BUTOXYCARBONYLAMINO-PROPIONIC ACID (S)-2-(((Benzyloxy)carbonyl)aMino)-3-((tert-butoxycarbonyl)aMino)propanoic acid L-ALANINE, 3-[[(1,1-DIMETHYLETHOXY)CARBONYL]AMINO]-N-[(PHENYLMETHOXY)CARBONYL]-
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CAS | 16947-84-5
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EINECS | 1533716-785-6 |
InChI | InChI=1/C16H22N2O6/c1-16(2,3)24-14(21)17-9-12(13(19)20)18-15(22)23-10-11-7-5-4-6-8-11/h4-8,12H,9-10H2,1-3H3,(H,17,21)(H,18,22)(H,19,20)/t12-/m0/s1 |
(S)-NA-CBZ-2-BOCAMINOMETHYLGLYCINE - Physico-chemical Properties
Molecular Formula | C16H22N2O6
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Molar Mass | 338.36 |
Density | 1.235±0.06 g/cm3(Predicted) |
Boling Point | 548.7±50.0 °C(Predicted) |
Flash Point | 285.6°C |
Vapor Presure | 7.12E-13mmHg at 25°C |
Appearance | White powder |
BRN | 3629152 |
pKa | 3.67±0.10(Predicted) |
Storage Condition | Sealed in dry,2-8°C |
Refractive Index | 1.533 |
MDL | MFCD00237342 |
(S)-NA-CBZ-2-BOCAMINOMETHYLGLYCINE - Risk and Safety
WGK Germany | 3 |
HS Code | 29242990 |
(S)-NA-CBZ-2-BOCAMINOMETHYLGLYCINE - Introduction
Z-Dap(Boc)-OH is an organic compound commonly abbreviated as Cbz-Boc-Dap. The following is a description of its nature, use, formulation and safety information:
Nature:
- Cbz-Boc-Dap is a white solid with good solubility.
-It is an amide compound with two amino groups and two protecting groups, namely N-Cbz(benzyloxycarbonyl) and N-Boc(tert-butoxycarbonyl) groups.
Use:
- Cbz-Boc-Dap is usually used as an intermediate in organic synthesis, especially as a reagent for protecting amino groups in peptide synthesis.
-It can undergo a chemical reaction under the protection of the amino group, and then remove the protecting group through appropriate conditions to obtain the desired product.
Method:
-The synthesis of Cbz-Boc-Dap can be completed through a series of chemical reaction steps.
-A commonly used synthesis method is to react 2,3-diaminopropionic acid with N-Cbz-iminoalcohol to obtain N-Cbz-2, 3-diaminopropanol. The product is then reacted with N-Boc tert-butyl carbamate, and the imino alcohol is removed by appropriate conditions, and the Cbz-Boc-Dap is finally obtained.
Safety Information:
-Laboratory safety measures, such as gloves, glasses and laboratory coats, are required when handling Cbz-Boc-Dap.
-Avoid inhaling its dust or contact with skin, eyes or mucous membranes.
-in storage and use, to be placed in a dry, cool, ventilated place, away from the fire and flammable materials.
-Detailed safety information and use recommendations can be found in the product's safety data sheet, and relevant instructions should be consulted and followed in advance.
Last Update:2024-04-09 15:17:53