(Z)-3-((3 - Names and Identifiers
(Z)-3-((3 - Physico-chemical Properties
Molecular Formula | C15H14N2O
|
Molar Mass | 238.28 |
Density | 1.256±0.06 g/cm3(Predicted) |
Melting Point | 226-228 °C |
Boling Point | 481.4±45.0 °C(Predicted) |
Solubility | Soluble in DMSO (5 mg/ml), and ethanol (100 mM). Insoluble in water. |
Appearance | Yellow orange solid |
Color | yellow to yellow orange |
pKa | 12.59±0.20(Predicted) |
Storage Condition | -20°C |
MDL | MFCD01940922 |
Use | It was used to study the mechanism of development of cerebral vasculature in zebrafish hindbrain,and study the pulmonary vascular remodeling in response to hypoxia in mouse model of pulmonary arterial hypertension. |
(Z)-3-((3 - Risk and Safety
Hazard Symbols | Xi - Irritant
|
Risk Codes | 36/37/38 - Irritating to eyes, respiratory system and skin.
|
Safety Description | S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.
S36 - Wear suitable protective clothing.
|
WGK Germany | 3 |
HS Code | 29339900 |
(Z)-3-((3 - Introduction
Semaxanib (SU5416) is a VEGFR(Flk-1/KDR) inhibitor with an IC50 of 1.23 μM, which is 20 times more inhibitory than PDGFRβ, and is inactive for EGFR,InsR and FGFR.
Last Update:2022-10-16 17:41:32