Molecular Formula | C6H10N6O |
Molar Mass | 182.18 |
Density | 1.3206 (rough estimate) |
Melting Point | 199-205°C |
Boling Point | 315.57°C (rough estimate) |
Flash Point | 229.734°C |
Water Solubility | Slightly soluble in water, DMSO and ethanol/n |
Solubility | Slightly soluble in water and ethanol, slightly soluble in dilute hydrochloric acid |
Vapor Presure | 0mmHg at 25°C |
Appearance | A loose lump or powder that is white, yellowish, or slightly reddish. |
Color | Off-White to Light Yellow |
Merck | 14,2798 |
pKa | pKa 4.42 (Uncertain) |
Storage Condition | 2-8°C |
Sensitive | Sensitive to heat and light |
Refractive Index | 1.7500 (estimate) |
MDL | MFCD00057167 |
Physical and Chemical Properties | Yellowish crystals or powder. The melting point was 205 °c, and 250-255 °c (decomposition) was also reported. Soluble in acid, slightly soluble in methanol, ethanol, insoluble in water. Thermal decomposition, unstable to acid and light. |
Use | Anti-tumor drugs, mainly used for melanoma, also used for soft tissue sarcoma and malignant lymphoma |
Risk Codes | R45 - May cause cancer R46 - May cause heritable genetic damage R20/21/22 - Harmful by inhalation, in contact with skin and if swallowed. R36/37/38 - Irritating to eyes, respiratory system and skin. |
Safety Description | S53 - Avoid exposure - obtain special instructions before use. S36/37/39 - Wear suitable protective clothing, gloves and eye/face protection. S45 - In case of accident or if you feel unwell, seek medical advice immediately (show the label whenever possible.) S37/39 - Wear suitable gloves and eye/face protection S36 - Wear suitable protective clothing. S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. |
WGK Germany | 3 |
RTECS | NI3950000 |
HS Code | 29349990 |
Reference Show more | 1. [IF=6.529] Gui Chen et al."Microbiome analysis combined with targeted metabolomics reveal immunological anti-tumor activity of icariside I in a melanoma mouse model."Biomed Pharmacother. 2021 Aug;140:111542 |