Name | Benzophenone hydrazone |
Synonyms | Benzophenone hydrazo diphenylketohydrazone BENZOPHENONE HYDROZONE Benzophenone hydrazone BENZOPHENONE HYDRAZONE diphenylketonehydrazone hydrazine of benzophenone diphenyl-methanonhydrazone benzophenoneimine n-amino- diphenylmethanone hydrazone diphenyl-methanone hydrazone diphenyldiazomethane precursor Di(phenyl)methylidenehydrazine (diphenylmethylidene)hydrazine Methanone, diphenyl-, hydrazone Ht--103 Benzophenonehydrazone (Bph) 3-iodo-N-({2-[4-(2-methylpropanoyl)piperazin-1-yl]phenyl}carbamothioyl)benzamide 3-iodo-N-[[2-[4-(2-methyl-1-oxopropyl)-1-piperazinyl]anilino]-sulfanylidenemethyl]benzamide |
CAS | 5350-57-2 |
EINECS | 226-321-8 |
InChI | InChI=1/C22H25IN4O2S/c1-15(2)21(29)27-12-10-26(11-13-27)19-9-4-3-8-18(19)24-22(30)25-20(28)16-6-5-7-17(23)14-16/h3-9,14-15H,10-13H2,1-2H3,(H2,24,25,28,30) |
InChIKey | QYCSNMDOZNUZIT-UHFFFAOYSA-N |
Molecular Formula | C13H12N2 |
Molar Mass | 196.25 |
Density | 1.1 |
Melting Point | 95-98 °C (lit.) |
Boling Point | 225-230 °C/55 mmHg (lit.) |
Flash Point | 146°C |
Solubility | Soluble in ether, benzene, chloroform and other organic solvents. |
Appearance | White crystal |
Color | White to yellow |
BRN | 1910177 |
pKa | 1.44±0.70(Predicted) |
Storage Condition | 2-8°C |
Refractive Index | 1.5014 (estimate) |
MDL | MFCD00007624 |
Physical and Chemical Properties | Melting Point: 95-98°C(lit.) Boiling Point: 225-230 ° C 55mm Hg(lit.) flash point: 146°C storage conditions: 0-6°C Properties: white crystals. |
Use | Used as organic pigments, pharmaceutical intermediates. |
WGK Germany | 3 |
RTECS | PC4954487 |
TSCA | Yes |
HS Code | 29280090 |
Raw Materials | Sulfuric acid hydrazine hydrate Benzophenone |
NIST chemical information | Information provided by: webbook.nist.gov (external link) |
EPA chemical information | Information provided by: ofmpub.epa.gov (external link) |
application | dibenzophenone hydrazone is an important raw material for the synthesis of photosensitive materials, fragrances and medicines, and is an intermediate for ultraviolet absorbers, organic pigments and pesticides. |
Preparation | CN200610051887 provides a simple operation, mild reaction conditions, high yield, easy availability of raw materials, low cost, and low environmental pollution. A method for synthesizing dibenzophenone hydrazone with lower concentration of hydrazine hydrate as raw material. The technical scheme adopted by the invention is as follows: a synthesis method of benzophenone hydrazone, in which benzophenone and hydrazine hydrate are reacted in an ionic liquid at 80-140 ℃ for 0.5-6h, and the reaction product is post-treated to obtain the dibenzophenone hydrazone shown, and the reaction formula is as follows: |
Use | Used as organic pigment and pharmaceutical intermediate Used in organic synthesis. |
production method | anhydrous ethanol solution of benzophenone is refluxed with anhydrous hydrazine for 10h, and dibenzophenone hydrazone is precipitated by cooling, with a yield of 87%. |