(s)-(+)-n,n-dimethyl-3-(1-naphthalenyloxy)-3-(2-thienyl)propanamine - Names and Identifiers
Name | (S)-(+)-N,N-Dimethyl-3-(1-naphthalenyloxy)-3-(2-thienyl)propanamine
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Synonyms | N-Methyl Duloxetine Duloxetine Impurity 11 S-(+)-N,N-DIMETHYL-3-(1-NAPHTHENYLOXY)-3-(2-THIENYL)PROPANAMINE N,N-dimethyl-3-naphthalen-1-yloxy-3-thiophen-2-ylpropan-1-amine (S)-(+)-N,N-Dimethyl-3-(1-phthalenyloxy)-3-(2-thienyl)propamine S-(+)-N,N-dimethyl-3-(1-naphthlenyloxy)-3-(2-thienyl)-propanamine (S)-(+)-N,N-Dimethyl-3-(1-naphthalenyloxy)-3-(2-thienyl)propanamine (s)-(+)-n,n-dimethyl-3-(1-naphthalenyloxy)-3-(2-thienyl)propanamine (3S)-N,N-dimethyl-3-naphthalen-1-yloxy-3-thiophen-2-ylpropan-1-amine (S)-(+)-N,N-DIMETHYL-3-(1-NAPHTHALENYLOXY)-3-(2-THIENYL)PROPANAMINE,ENTERPRISE STANDARD
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CAS | 132335-46-7
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(s)-(+)-n,n-dimethyl-3-(1-naphthalenyloxy)-3-(2-thienyl)propanamine - Physico-chemical Properties
Molecular Formula | C19H21NOS
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Molar Mass | 311.44 |
Density | 1.146 |
Boling Point | 459.7±40.0 °C(Predicted) |
pKa | 9.19±0.28(Predicted) |
Storage Condition | 2-8°C |
(s)-(+)-n,n-dimethyl-3-(1-naphthalenyloxy)-3-(2-thienyl)propanamine - Introduction
S-(+)-N, N-dimethyl-3-(1-naphthyloxy)-3-(2-thiophene)-propylamine is a chemical compound, also known as NMTD, whose chemical name is (1R,2S)-3-[(1-naphthyloxy) methyl]-2-[(2-thienyl) methyl]-1-amine.
Properties of the compound include:
1. appearance: colorless or light yellow liquid.
2. Solubility: Soluble in most organic solvents, such as ethanol, chloroform, dimethyl sulfoxide, etc.
3. melting point: about -30 ℃.
S-( )-N, N-dimethyl-3-(1-naphthoxy)-3-(2-thiophene)-propylamine has certain applications in the field of pharmaceutical research, mainly used as an intermediate for the synthesis of chiral antidepressants. It can be used as a synthetic precursor for selective 5-HT2A receptor antagonists. In addition, it is also used in the preparation of some other drugs and medical products.
The compound can be produced by chemical synthesis. A common preparation method is to react the synthetic chiral intermediate with the appropriate amide and purify the target compound by crystallization. Specific synthetic routes and conditions can be optimized according to specific requirements.
The following safety information is required when using and handling S-( )-N, N-dimethyl-3-(1-naphthyloxy)-3-(2-thiophene)-propylamine:
1. Use should wear appropriate protective equipment, such as eye protection and respiratory protection.
2. avoid direct contact with the skin, such as contact should immediately rinse with plenty of water and soap.
3. avoid inhalation or ingestion, such as inadvertent inhalation or ingestion, should immediately seek medical attention.
4. in the process of operation to avoid dust, smoke or steam.
This safety information is for reference only. When using and handling the compound, the corresponding safety operation procedures and guidelines should be followed according to the actual situation.
Last Update:2024-04-09 21:21:28