(s)-2-((((9H-芴-9-基)甲氧基)羰基)(甲基)氨基)-2-苯乙酸

(s)-2-((((9H-芴-9-基)甲氧基)羰基)(甲基)氨基)-2-苯乙酸 - Names and Identifiers

Name	Fmoc-Nalpha-methyl-L-phenylglycine
Synonyms	FMOC-MEPHG-OH FMOC-L-MEPHG-OH FMOC-N-ME-PHG-OH FMOC-N-METHYL-L-PHENYLGLYCINE Fmoc-Nalpha-methyl-L-phenylglycine FMOC-N-ALPHA-METHYL-L-PHENYLGLYCINE N-FMoc-(S)-a-(MethylaMino)-benzeneacetic acid N-ALPHA-(9-FLUORENYLMETHOXYCARBONYL)-N-ALPHA-METHYL-L-PHENYLGLYCINE N-ALPHA-(9-FLUORENYLMETHYLOXYCARBONYL)-N-ALPHA-METHYL-L-PHENYLGLYCINE
CAS	574739-36-9

(s)-2-((((9H-芴-9-基)甲氧基)羰基)(甲基)氨基)-2-苯乙酸 - Physico-chemical Properties

Molecular Formula	C24H21NO4
Molar Mass	387.43
Density	1.281±0.06 g/cm3(Predicted)
Boling Point	580.4±39.0 °C(Predicted)
pKa	3.41±0.10(Predicted)
Storage Condition	Sealed in dry,2-8°C
Sensitive	Irritant
MDL	MFCD01861296

(s)-2-((((9H-芴-9-基)甲氧基)羰基)(甲基)氨基)-2-苯乙酸 - Risk and Safety

Hazard Class

IRRITANT

(s)-2-((((9H-芴-9-基)甲氧基)羰基)(甲基)氨基)-2-苯乙酸 - Introduction

(s)-2-((((9H-fluoren-9-yl) methoxy) carbonyl) (methyl) amino)-2-phenylacetic acid (Fmoc-Nalpha-methyl-L-phenylglycine), also known as Fmoc-N α-methyl-L-phenylglycine, is an organic compound.

Nature:
Fmoc-Nα-methyl-L-phenylglycine is a white crystalline solid with high solubility. It is stable in the environment, but sensitive to light and heat.

Use:
Fmoc-Nα-methyl-L-phenylglycine is an important amino acid derivative, which is widely used in peptide synthesis and protein engineering. It is commonly used as a protecting group to protect the carboxyl group of an amino acid during peptide synthesis to prevent non-specific reactions from occurring.

Preparation Method:
The preparation of Fmoc-Nα-methyl-L-phenylglycine can be achieved by a variety of methods, one of which is to introduce Fmoc protecting group by reacting Fmoc-OSu(N-9-fluorenyl-amino acid chloromethyl ester) on Nα-methyl-L-phenylglycine.

Safety Information:
Fmoc-Nα-methyl-L-phenylglycine is relatively safe to use under normal operating conditions, but care should be taken to avoid inhaling dust or contacting skin and eyes during use. For the use of any chemical, it should be strictly operated in accordance with safe operating procedures and follow personal protective measures. Appropriate laboratory equipment and training should be available when handling the compound to ensure safety and proper disposal measures.

Last Update：2024-04-09 02:00:56