(s)-2-amino-3-hydroxypropanoicacid
L-Serine
CAS: 56-45-1
Molecular Formula: C3H7NO3
(s)-2-amino-3-hydroxypropanoicacid - Names and Identifiers
| Name | L-Serine |
| Synonyms | Ser Serine L-Serine H-Ser-OH L-(+)-SERINE L-(-)-SERINE 3-Hydroxy-alanine L-Serine, USP Grade 8-HYDROXY-L-ALANINE 2-Amion-3-hydroxypropionicacid L-2-Amino-3-hydroxypropionic acid (s)-2-amino-3-hydroxypropanoicacid (S)-2-Amino-3-hydroxypropionic acid (S)-2-Amino-3-hydroxypropanoic acid alpha-amino-beta-hydroxypropionicacid alpha-Amino-beta-hydroxypropionic acid Propanoic acid, 2-amino-3-hydroxy-, (S)- |
| CAS | 56-45-1 |
| EINECS | 200-274-3 |
| InChI | InChI=1/C3H7NO3/c4-2(1-5)3(6)7/h2,5H,1,4H2,(H,6,7)/t2-/m0/s1 |
| InChIKey | MTCFGRXMJLQNBG-REOHCLBHSA-N |
(s)-2-amino-3-hydroxypropanoicacid - Physico-chemical Properties
| Molecular Formula | C3H7NO3 |
| Molar Mass | 105.09 |
| Density | 1.6 |
| Melting Point | 222 °C (dec.) (lit.) |
| Boling Point | 197.09°C (rough estimate) |
| Specific Rotation(α) | 15.2 º (c=10, 2N HCl) |
| Flash Point | 150°C |
| Water Solubility | 250 g/L (20 ºC) |
| Solubility | Soluble in water (20°C,25g/100ml water) and inorganic acid, insoluble in organic solvents, absolute ethanol, ether and benzene |
| Appearance | Hexahedral flake crystal or prismatic crystal |
| Color | White |
| Maximum wavelength(λmax) | λ: 260 nm Amax: 0.05λ: 280 nm Amax: 0.05 |
| Merck | 14,8460 |
| BRN | 1721404 |
| pKa | 2.19(at 25℃) |
| PH | 5-6 (100g/l, H2O, 20℃) |
| Storage Condition | 2-8°C |
| Stability | Stable. Incompatible with strong oxidizing agents. |
| Refractive Index | 1.4368 (estimate) |
| MDL | MFCD00064224 |
| Physical and Chemical Properties | Traits: hexagonal lamellar crystals or prismatic crystals. Melting Point: 223-228 ℃ (decomposition) solubility: soluble in water (20 ℃,25g/mL). |
| Use | Used as biochemical reagents and food additives |
(s)-2-amino-3-hydroxypropanoicacid - Risk and Safety
| Hazard Symbols | Xi - Irritant |
| Risk Codes | 36/37/38 - Irritating to eyes, respiratory system and skin. |
| Safety Description | S24/25 - Avoid contact with skin and eyes. S36 - Wear suitable protective clothing. S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. |
| WGK Germany | 3 |
| RTECS | VT8100000 |
| FLUKA BRAND F CODES | 3 |
| TSCA | Yes |
| HS Code | 29225000 |
| Toxicity | 可安全用于食品(FDA，§172．320，2000)。 |
(s)-2-amino-3-hydroxypropanoicacid - Nature
Open Data Verified Data
- This product is white crystal or crystalline powder; Odorless, sweet. Soluble in water (5%,25 ° C), almost insoluble in ethanol, acetone or ether. Decomposition at 228 °c. High vacuum (0. 013Pa), 150 deg C can sublimation.
- serine is a non-essential amino acid, a sugar-producing amino acid. It can be synthesized in vivo from D-glyceric acid as a precursor. Threonine, glycine can be converted into serine, serine can also be converted into glycine. In vivo, serine participates in the transformation of-SH and-OH groups and the biosynthesis of purine pyrimidines and trines, which can be converted into choline and phospholipid components. Has special wettability. The content of protein in sericin was rich, and 13. 64% in cocoon coat.
Last Update：2024-01-02 23:10:35
(s)-2-amino-3-hydroxypropanoicacid - Preparation Method
Open Data Verified Data
- hydrolysis method
- fermentation by adding precursors
- chemical synthesis (1) production using hydroxyacetaldehyde as a raw material (2) using a vinyl compound as a raw material.
- The enzymatic method uses DL-2-oxoioxazolidine-4 monocarboxylic acid (DL-OOC), an intermediate of chemical synthesis of DL-serine, serine can be produced using L-OOC hydrolase produced by P. Testosterone or OOC racemase produced from B. Subtilis.
Last Update：2022-01-01 11:10:01
(s)-2-amino-3-hydroxypropanoicacid - Use
Open Data Verified Data
amino acid drugs. Mainly used for amino acid infusion, due to special wettability, also used in cream, cosmetics.
Last Update：2022-01-01 11:10:01
(s)-2-amino-3-hydroxypropanoicacid - Safety
Open Data Verified Data
light shielding, closed storage.
Last Update：2022-01-01 11:10:01
(s)-2-amino-3-hydroxypropanoicacid - Introduction
L-Serine is a natural amino acid, which is an important part of protein synthesis in vivo. Its chemical formula is C3H7NO3 and its molecular weight is 105.09g/mol.
L-Serine have the following properties:
1. Appearance: colorless crystal or white crystalline powder;
2. Solubility: soluble in water, slightly soluble in alcohol, almost insoluble in ether and ether solvents;
3. melting point: about 228-232 ℃;
4. taste: with a slightly sweet taste.
L-Serine play important roles in biology, such:
1. protein synthesis: as a kind of amino acid, L-Serine is an important part of protein synthesis, involved in cell growth, repair and metabolism;
2. Biocatalyst: L-Serine is a kind of biocatalyst, which can be used to synthesize bioactive compounds, such as enzymes and drugs.
L-Serine can be prepared by two methods: synthesis and extraction:
1. Synthesis method: L-Serine can be synthesized by synthetic reaction. Common synthesis methods include chemical synthesis and enzyme catalysis;
2. Extraction method: L-Serine can also be extracted from natural materials, such as bacteria, fungi or plants through fermentation.
Regarding safety information, L-Serine is an essential amino acid for the human body and is generally considered safe. However, excessive intake may cause some side effects, such as gastrointestinal discomfort and allergic reactions. In people with severe allergies, exposure to L-Serine may trigger an allergic reaction. When using L-Serine, it is recommended to use according to the advice of doctors or professionals, and strictly control the dosage.
L-Serine have the following properties:
1. Appearance: colorless crystal or white crystalline powder;
2. Solubility: soluble in water, slightly soluble in alcohol, almost insoluble in ether and ether solvents;
3. melting point: about 228-232 ℃;
4. taste: with a slightly sweet taste.
L-Serine play important roles in biology, such:
1. protein synthesis: as a kind of amino acid, L-Serine is an important part of protein synthesis, involved in cell growth, repair and metabolism;
2. Biocatalyst: L-Serine is a kind of biocatalyst, which can be used to synthesize bioactive compounds, such as enzymes and drugs.
L-Serine can be prepared by two methods: synthesis and extraction:
1. Synthesis method: L-Serine can be synthesized by synthetic reaction. Common synthesis methods include chemical synthesis and enzyme catalysis;
2. Extraction method: L-Serine can also be extracted from natural materials, such as bacteria, fungi or plants through fermentation.
Regarding safety information, L-Serine is an essential amino acid for the human body and is generally considered safe. However, excessive intake may cause some side effects, such as gastrointestinal discomfort and allergic reactions. In people with severe allergies, exposure to L-Serine may trigger an allergic reaction. When using L-Serine, it is recommended to use according to the advice of doctors or professionals, and strictly control the dosage.
Last Update：2024-04-09 20:13:35
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