,-Diphenyl-butyrolactone
Alpha,Alpha-Diphenyl-Gamma-Butyrolactone
CAS: 956-89-8
Molecular Formula: C16H14O2
,-Diphenyl-butyrolactone - Names and Identifiers
,-Diphenyl-butyrolactone - Physico-chemical Properties
| Molecular Formula | C16H14O2 |
| Molar Mass | 238.28 |
| Density | 1.173±0.06 g/cm3(Predicted) |
| Melting Point | 77-79°C(lit.) |
| Boling Point | 411.2±45.0 °C(Predicted) |
| BRN | 197879 |
| MDL | MFCD00005393 |
| Physical and Chemical Properties | Crystalline compound. Melting point 77-79 ℃. |
,-Diphenyl-butyrolactone - Risk and Safety
| Safety Description | 24/25 - Avoid contact with skin and eyes. |
| WGK Germany | 3 |
| HS Code | 29322985 |
,-Diphenyl-butyrolactone - References
| Overview | tetrahydrofuran derivatives are important organic intermediates that exist in many natural products has gradually become the focus of attention of workers in the field of organic synthesis and medicinal chemistry. At present, 2, 5-disubstituted tetrahydrofuran derivatives are mainly synthesized by various organometallic reagents (such as Al, Ti, Sn, Li, Mg, Si, etc.). The method of synthesizing 2, 5-disubstituted tetrahydrofuran derivatives by using monoalkyl zinc halide has explored another route for synthesizing 2, 5-disubstituted tetrahydrofuran derivatives. Α, α-diphenyl-γ-butyrolactone is one of tetrahydrofuran derivatives. |
| Use | an intermediate of loperamide. |
| production method | α-bromophenylacetonitrile is brominated with phenylacetonitrile and then condensed with benzene in the presence of anhydrous aluminum chloride, diphenylacetonitrile was obtained, and the latter was reacted with ethylene oxide under the action of sodium amino acid to obtain the product. |
Last Update：2024-04-09 21:11:58
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CAS: 956-89-8
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