-3-(2,4,5-trifluorophenyl) - Names and Identifiers
Name | boc-d-2,4,5-trifluorophenylalanine
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Synonyms | Boc-D-2,4,5-Trifluorophe BOC-D-2,4,5-TRIFLUOROPHE -3-(2,4,5-trifluorophenyl) BOC-D-2,4,5-TRIFLUOROPHENYLALANINE boc-d-2,4,5-trifluorophenylalanine Boc-D-2-Amino-3-(2,4,5-trifluoro-phenyl)alanine (R)-N-(TERT-BUTOXYCARBONYL)-2,4,5-TRIFLUOROPHENYLALANINE (R)-2-((tert-Butoxycarbonyl)aMino)-3-(2,4,5-trifluorophenyl)propanoic acid (2R)-2-[(TERT-BUTOXYCARBONYL)AMINO]-3-(2,4,5-TRIFLUOROPHENYL)PROPANOIC ACID
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CAS | 486460-09-7
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-3-(2,4,5-trifluorophenyl) - Physico-chemical Properties
Molecular Formula | C14H16F3NO4
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Molar Mass | 319.28 |
Density | 1.323±0.06 g/cm3(Predicted) |
Boling Point | 424.7±45.0 °C(Predicted) |
Appearance | Solid |
pKa | 3.79±0.14(Predicted) |
Storage Condition | 2-8°C |
-3-(2,4,5-trifluorophenyl) - Introduction
boc-d-2,4,5-trifluorophenylalanine is an amino acid compound in which the amino acid moiety in the structure is alanine and the aromatic ring moiety has three fluorine atoms in place of the benzene ring. The following is a description of its nature, use, preparation and safety information:
Nature:
-Appearance: Generally colorless or white solid.
-Solubility: Easily soluble in some organic solvents, such as dimethyl sulfoxide (DMSO) and dimethyl formamide (DMF).
-Stability: It is relatively stable under dry conditions, but it is easy to absorb moisture in a humid environment.
-Reactivity: Due to the fluorine atom of the aromatic ring part, boc-d-2,4,5-trifluorophenylalanine exhibits special reactivity in some organic reactions.
Use:
- boc-d-2,4,5-trifluorophenylalanine is commonly used in the field of solid phase synthesis and peptide synthesis as a raw material for the synthesis of polypeptides.
-Due to the introduction of three fluorine atoms on its aromatic ring, boc-d-2,4,5-trifluorophenylalanine enhances the interaction between polypeptides and receptors, so it is used in the field of research on biological activity and drug design.
Preparation Method:
-The preparation of boc-d-2,4,5-trifluorophenylalanine can be obtained by chemical synthesis. A common synthesis method is to first synthesize D-alanine difluorobenzoate and then react in the presence of the amino protecting agent Boc(tert-butoxycarbonyl) to obtain the target product.
Safety Information:
- boc-d-2,4,5-trifluorophenylalanine has not been extensively studied, so there is a lack of specific safety data.
-As organic compounds, they should be considered potentially dangerous and avoid contact with skin and inhalation.
-When handling this compound, follow laboratory safety procedures and store and dispose of it in an appropriate manner.
Please note that the above information is for reference only, and follow the safety procedures and relevant regulations when using this compound.
Last Update:2024-04-09 21:04:16