Name | Diethylnirtosamine |
Synonyms | DEN DENA den(mutagen) Diaethylnitrosamin Diethylnirtosamine N-NITROSODIETHYLAMINE N,N-DIETHYLNITROSOAMINE 1,1-Diethyl-2-oxohydrazine |
CAS | 55-18-5 |
EINECS | 200-226-1 |
InChI | InChI=1S/C4H10N2O/c1-3-6(4-2)5-7/h3-4H2,1-2H3 |
Molecular Formula | C4H10N2O |
Molar Mass | 102.14 |
Density | 0.95 g/mL (lit.) |
Melting Point | <25℃ |
Boling Point | 177 °C (lit.) |
Water Solubility | 106.2g/L(24 ºC) |
Vapor Presure | 1.7 mmHg at 20 °C |
Appearance | Form liquid, color yellow |
pKa | -3.14±0.70(Predicted) |
Storage Condition | 2-8°C |
Stability | Stable, but light sensitive. Combustible. Incompatible with strong oxidizing agents, reducing agents. |
Refractive Index | n20/D 1.437 |
MDL | MFCD00013890 |
Physical and Chemical Properties | Bioactive N-Nitrosodiethylamine is an effective carcinogen dialkylnitramine. N-Nitrosodiethylamine are mainly found in tobacco smoke, water, cheddar cheese, pickled foods, fried foods and many alcoholic beverages. N-Nitrosodiethylamine are responsible for changes in ribozyme related to DNA repair/replication. N-Nitrosodiethylamine can cause various tumors in all animals. The main target organs are nasal cavity, trachea, lung, esophagus and liver. |
Use | Use research is used for carcinogens of all animal species. The main target organs are nasal acupoints, trachea, lung, esophagus and liver. It is also used in organic synthesis. |
Risk Codes | R45 - May cause cancer R22 - Harmful if swallowed R39/23/24/25 - R23/24/25 - Toxic by inhalation, in contact with skin and if swallowed. R11 - Highly Flammable |
Safety Description | S53 - Avoid exposure - obtain special instructions before use. S45 - In case of accident or if you feel unwell, seek medical advice immediately (show the label whenever possible.) S36/37 - Wear suitable protective clothing and gloves. S16 - Keep away from sources of ignition. |
UN IDs | UN 2810 6.1/PG 3 |
WGK Germany | 3 |
RTECS | IA3500000 |
HS Code | 29299090 |
Hazard Class | 6.1(b) |
Packing Group | III |
Toxicity | LD50 oral (rat) 280 mg/kg |
Odor | Not available |
Merck | 6636 |
BRN | 1744991 |
(IARC) Carcinogen Classification | 2A (Vol. 17, Sup 7) 1987 |
EPA chemical information | N-Nitrosodiethylamine (55-18-5) |
toxic substance data | 55-18-5(Hazardous Substances Data) |