1,10-Diaza-18-crown-6

1,10-Diaza-18-crown-6 - Names and Identifiers

Name	1,4,10,13-tetraoxa-7,16-diazacyclooctadecane
Synonyms	1,10-Diaza-18-crown-6 4,13-DIAZA-18-CROWN-6 1,10-DIAZA-18-CROWN-6 KRYPTOFIX 22 FOR SYNTHESIS 4,13-DIAZA-18-CROWN 6-ETHER 1,4,10,13-tetraoxa-7,16-diazacyclooctadecane 1,4,10,13-TETRAOXA-7,16-DIAZACYCLOOCTADECANE 1,4,10,13-tetraoxa-7,16-diazoniacyclooctadecane KRYPTOFIX 22 POLYMER (SILICA GEL) FOR SYNTHESIS
CAS	23978-55-4 29296-32-0
EINECS	245-965-0
InChI	InChI=1/C12H26N2O4/c1-5-15-9-10-17-7-3-14-4-8-18-12-11-16-6-2-13-1/h13-14H,1-12H2/p+2

1,10-Diaza-18-crown-6 - Physico-chemical Properties

Molecular Formula	C12H26N2O4
Molar Mass	262.35
Density	1.0807 (rough estimate)
Melting Point	111-114°C(lit.)
Boling Point	405.6°C (rough estimate)
Flash Point	170.6°C
Water Solubility	Soluble in water.
Vapor Presure	5.33E-07mmHg at 25°C
Appearance	Shiny Crystalline Powder
Color	Off-white
BRN	609764
pKa	9.00±0.20(Predicted)
Storage Condition	Store below +30°C.
Refractive Index	1.4560 (estimate)
MDL	MFCD00005112

1,10-Diaza-18-crown-6 - Risk and Safety

Hazard Symbols	Xi - Irritant
Risk Codes	36/37/38 - Irritating to eyes, respiratory system and skin.
Safety Description	S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. S37/39 - Wear suitable gloves and eye/face protection S37 - Wear suitable gloves.
WGK Germany	2
RTECS	HM1650000
FLUKA BRAND F CODES	10
HS Code	2934 99 90
Toxicity	LD50 orally in Rabbit: 3400 mg/kg

1,10-Diaza-18-crown-6 - Introduction

1,4,10,13-tetraoxa-7,16-diazacyclooctadecane is a macrocyclic compound with an 18-atom composition and the chemical formula C12H24N2O4. Its properties are as follows:

1. Solubility: 1,4,10,13-tetraoxa-7,16-diazacyclooctadecane has good solubility in water and can also be dissolved in some organic solvents.

2. Stability: It is stable at room temperature, but may decompose under the action of high temperature or oxidant.

3. Coordination: 1,4,10,13-tetraoxa-7,16-diazacyclooctadecane is a molecule that can form coordination complexes with metal ions. It forms stable complexes with some metal ions such as sodium, potassium and rubidium ions.

use, 1,4,10,13-tetraoxa-7,16-diazacyclooctadecane is mainly used in the field of coordination chemistry and chemical analysis. It is often used as a recognition and separation reagent for metal ions, and can also be used in electrochemistry and photochemistry.

on the preparation method, the synthesis of 1,4,10,13-tetraoxa-7,16-diazacyclooctadecane is more complicated, usually by reacting a kind containing 1, the amine of the 2-epoxy butane ring is reacted with cyclohexadienyl ketone.

In terms of safety information, 1,4,10,13-tetraoxa-7,16-diazacyclooctadecane is generally safe under normal use conditions. However, as a chemical reagent, it is still necessary to comply with the necessary safety procedures, such as wearing protective glasses and gloves, to avoid inhalation and contact with the skin. In addition, it should be stored in a dry, cool and well-ventilated place to avoid contact with strong oxidants.

Last Update：2024-04-10 22:31:16