1,2-Benzenedialdehyde

1,2-Benzenedialdehyde - Names and Identifiers

Name	1,2-Phthalic dicarboxaldehyde
Synonyms	OPA phthalaldehyde O-PHTALALDEHYDE o-phthaladehyde Phthaldialdehyde O-PHTHALALDEHYDE o-Phthaldialdehyde 1,2-Benzenedialdehyde o-Phthaldialdehyde OPD o-Phthalaldehyde (1.11452) benzene-1,2-dicarbaldehyde o-Phthalic dicarboxaldehyde Benzene-1,2-dicarboxaldehyde 1,2-Phthalic dicarboxaldehyde
CAS	643-79-8
EINECS	211-402-2
InChI	InChI=1/C8H6O2/c9-5-7-3-1-2-4-8(7)6-10/h1-6H

1,2-Benzenedialdehyde - Physico-chemical Properties

Molecular Formula	C8H6O2
Molar Mass	134.13
Density	1.189g/cm³
Melting Point	54-57℃
Boling Point	266.1°C at 760 mmHg
Flash Point	98.5°C
Water Solubility	soluble
Solubility	Soluble in water, ethanol, ether and organic solvents, slightly soluble in petroleum ether.
Vapor Presure	0.0088mmHg at 25°C
Appearance	Light yellow crystalline powder
Storage Condition	2-8 ℃, dark
Sensitive	`sensitive` to air, light and humidity
Refractive Index	1.622
MDL	MFCD00003335
Physical and Chemical Properties	Density 1.13 melting point 54-57°C boiling point 83-84°C (0.7501 mmHg) flash point 132°C water-soluble solution
Use	Mainly used in medicine, dyes, etc

1,2-Benzenedialdehyde - Risk and Safety

Hazard Symbols	T - Toxic
Risk Codes	R25 - Toxic if swallowed R34 - Causes burns R43 - May cause sensitization by skin contact
Safety Description	S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. S36/37/39 - Wear suitable protective clothing, gloves and eye/face protection. S45 - In case of accident or if you feel unwell, seek medical advice immediately (show the label whenever possible.)
UN IDs	UN2923 8/PG 2

1,2-Benzenedialdehyde - Upstream Downstream Industry

Downstream Products

Pentacene
Lacidipine
NAPHTHALENE-2,3-DICARBOXALDEHYDE
Doxepin hydrochloride
2H-Isoindole
2,3-NAPHTHALENEDICARBOXYLIC ACID DIMETHYL ESTER
3-Isoquinolinecarbonitrile
PHTHALAMIDE
2,3-DICHLORONAPHTHALENE
2,3-NAPHTHALENEDICARBOXYLIC ANHYDRIDE
1,2-Benzenedimethanol
DIBENZYL PHTHALATE
Methyl 3-isoquinolinecarboxylate

1,2-Benzenedialdehyde - Reference

Reference

1. Luo Yuting, Wu, Bao-Sen Valley, the sea, etc. Characteristics and antioxidant activity of crude peptides from Norton fire legs in different processing years [J]. Meat Research 2017(09):32-37.
2. Ding Fan, Liu, Qing, Hua Wang, Quan Jie. Preparation of low-ash industrial protein powder and its paper sizing performance [J]. China leather 2020 49(05):7-15.
3. Zhang Sirui, Guo Aohuan, Han Ying, GE Shuhua, Wang Jian, Xu Zihao. Study on preparation of peptide calcium phosphate from waste protein [J]. Leather and chemical industry, 2019, 36(04):9-13.
4. Wang Mingying, GE Shuhua, Yuan Yan, et al. Study on the preparation process of different molecular weight peptide-Zn chelate by leather waste [J]. Leather and Chemical Industry 2020 v.37;No.189(01):7-14 34.
5. GE Shuhua, Yu Yujun, et al. Study on preparation of peptide Ca chelate from leather waste [J]. Soil Bulletin 2019 v.50;No.300(03):206-214.
6. Luo Yanhua, Chen Pei, Hai Wang, Quan Jie. Study on preparation of N-oleoyl compound polypeptide surfactant from Chrome-containing leather shavings [J]. Leather and chemical industry 2017(4).
7. Liu rongmeitian, Yuan Yuan, Geng Qi, et al. Isolation, identification and functional study of lactic acid bacteria from Sichuan Daicheng traditional cheese [J]. China test 2017v.43;No.233(12):58-62.
8. Chen Peiyun, Wang Xianyou, Zhilei Zhao, et al. Identification of Gynostemma pentaphyllum from different habitats by HPLC fingerprint of amino acids [J]. Food Research and Development, 2015(12):94-98.
9. Chen Peiyun, Gong Dongjun, Zhao Zhilei, et al. Study on fingerprint of amino acids in Gynostemma pentaphyllum from Pingli, Shaanxi province [J]. Science and Technology of food industry, 2014, 035(006):67-72.
10. Luo Yanhua, Wang Quanjie, Chen Peihai, et al. Determination of degree of hydrolysis of protein hydrolysates [J]. Leather and chemical industry, 2017, 02:32-37.
11. Wu Baosen, Gu Dahai, Wang Guiying, et al. Antioxidant activity and sodium nitrite scavenging activity of crude peptide from Norton fire leg [J]. Meat Research, 2017, 31(008):6-11.
12. Luo Yanhua, Wang, Quan Jie, Chen Peihai. Comparison of the effect of CaO and NaOH on the hydrolysis of Chrome shavings [J]. Leather and chemical industry 2017 034(003):1-12.
13. Ding Fan, Ji Xiang-hui, Duan Bao-rong, Wang Quan-Jie. Study on preparation of industrial protein powder from waste Chrome shavings [J]. Leather chemical industry, 2020,37(05):10-15 20.
14. Huang, Yanming. Study on degradation mechanism and texture protection of Procambarus clarkii at high temperature [D]. Hubei University of Technology, 2020.
15. Xu Xikai, Xin Jiaying, Ren Jiaxin, Han Ye, Wang Guangjiao, Cui Tianyu. Preparation and physicochemical properties of soluble dietary fiber from wheat bran fermented by Neurospora [J]. Science and Technology of food industry, 2021,42(02):170-176 191.[6] ji xin, Liu Xiao-Qian, Gao Lu, Xiao Su-ping, Liang Yao-hua, Li Chun, Wang Zhi-min. Qualitative and Quantitative Analysis of triterpenoids in fructus Ligustri Lucidi [J]. Chinese Journal of Traditional Chinese Medicine, 2021,46(05):1168-1178.
16. [IF = 3.067] Xiaoyu Wen et al."Transglutaminase induced gels using bitter apricot kernel protein: Chemical, textural and release properties."Food Biosci. 2018 Dec;26:15
17. [IF=4.952] Feng Xue et al."Prevention of frozen-dough from deterioration with incorporation of glutenin-polyphenols conjugates prepared by ultrasound."Lwt Food Sci Technol. 2021 Nov;151:112141
18. [IF=2.659] G.Y. Xiong et al."Process optimization and the relationship between the reaction degree and the antioxidant activity of Maillard reaction products of chicken liver protein hydrolysates."Poultry Sci. 2020 Jul;99:3733
19. [IF=1.984] Guanhao Bu et al."Functional characteristics and structural properties of soybean protein isolate-maltose conjugates."Cereal Chemistry. 2021 May 30
20. [IF=4.952] Xiao Jia et al."Glycation of rice protein and d-xylose pretreated through hydrothermal cooking-assisted high hydrostatic pressure: Focus on the structural and functional properties."Lwt Food Sci Technol. 2022 Apr;160:113194
21. [IF=6.576] Jin Wang et al."Effect of Frying Process on Nutritional Property, Physicochemical Quality, and in vitro Digestibility of Commercial Instant Noodles."Front Nutr. 2022; 9: 823432
22. [IF=5.396] Ge Ge et al."Green tea polyphenols bind to soy proteins and decrease the activity of soybean trypsin inhibitors (STIs) in heated soymilk."Food & Function. 2022 May ;:

1,2-Benzenedialdehyde - Introduction

1, chemical field analysis reagents: as amine alkaloid reagents, used for fluorescence determination of primary amines and peptide bond decomposition products. 2. Organic synthesis: It is also a pharmaceutical intermediate. 3. Fluorescent reagent, used for pre-column HPLC separation of amino acid derivatives, flow cytometry to measure the thiol groups of proteins.

Last Update：2022-10-16 17:27:41

1,2-Benzenedialdehyde - Security information

WGK Germany	3
RTECS number	TH6950000
F	1-8-10
auto-ignition temperature	480 °C
Hazard Note	Irritant/Air Sensitive
TSCA	Yes
HazardClass	8
PackingGroup	Ⅱ
customs code	29122900
toxic substance data	643-79-8(Hazardous Substances Data)
Toxicity	LD50 orally in Rabbit: 178 mg/kg LD50 dermal Rat > 2000 mg/kg

Last Update：2024-04-10 22:29:15

1,2-Benzenedialdehyde - Nature

storage conditions	2-8°C
solubility	The solubility of o-phthalaldehyde is 3g/100 mL diisopropyl ether, 5g/100mL deionized water, 20g/100mL chloroform, or 20g/100mL acetone at 20°C.
morphology	powder
color	yellow
PH value	7 (53g/l, H2O, 20℃)
water solubility	soluble
sensitivity	Air Sensitive
Merck	14,7368
BRN	878317
stability	Stable. Air sensitive. Incompatible with strong oxidizing agents, strong bases.
InChIKey	ZWLUXSQADUDCSB-UHFFFAOYSA-N
NIST chemical information	O-phthalaldehyde(643-79-8)
EPA chemical information	1,2-Benzenedicarboxaldehyde (643-79-8)

Last Update：2024-04-09 20:52:54

1,2-Benzenedialdehyde - Uses and synthesis methods

Chemical properties

Yellow needle crystals. Melting point 54-56 ℃.

Uses

1. This product is a pharmaceutical intermediate. It is the latest external efficient and safe antibacterial disinfectant. It is used as a disinfection and sterilization of endoscopic surgical instruments in hospitals. It can be used to synthesize a new anti-platelet aggregation drug indolebofen. It is also an analytical reagent in the chemical field.

3, yellow needle crystal, mainly used in medicine, dyes, etc. Amino acid derivative reagent, fluorescence detection, the reaction can be completed in one minute, but the product is unstable and needs to be detected immediately.

4, mainly used in medicine, dyes, amino acid derivative reagents, etc.

5, amine alkaloid reagents, used for fluorescence determination of primary amines and peptide bond decomposition products. Organic synthesis.?

6. Reagents for amine alkaloids, used for fluorescence determination of primary amines and peptide bond decomposers; suitable for pre-column derivatization of amino acids in high performance liquid chromatography separation; used for measurement of protein sulfhydryl by flow cytometry

7, 1 chemical field analysis reagent: as an amine alkaloid reagent, used for fluorescence determination of primary amines and peptide bond decomposition products. 2. Organic synthesis: It is also a pharmaceutical intermediate 3. Fluorescent reagent, used for pre-column HPLC separation of amino acid derivatives, flow cytometry to measure the thiol groups of proteins.

8, for medical inspection

Last Update：2024-04-09 19:04:55

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1,2-Benzenedialdehyde

Downstream Products for 1,2-Benzenedialdehyde

Pentacene
Lacidipine
NAPHTHALENE-2,3-DICARBOXALDEHYDE
Doxepin hydrochloride
2H-Isoindole
3-Isoquinolinecarbonitrile
PHTHALAMIDE
2,3-NAPHTHALENEDICARBOXYLIC ANHYDRIDE
1,2-Benzenedimethanol
DIBENZYL PHTHALATE
Methyl 3-isoquinolinecarboxylate

1,2-Benzenedialdehyde

1,2-Phthalic dicarboxaldehyde

CAS: 643-79-8

Molecular Formula: C8H6O2

1,2-Benzenedialdehyde - Names and Identifiers

1,2-Benzenedialdehyde - Physico-chemical Properties

1,2-Benzenedialdehyde - Risk and Safety

1,2-Benzenedialdehyde - Upstream Downstream Industry

1,2-Benzenedialdehyde - Reference

1,2-Benzenedialdehyde - Introduction

1,2-Benzenedialdehyde - Security information

1,2-Benzenedialdehyde - Nature

1,2-Benzenedialdehyde - Uses and synthesis methods

Supplier List

1,2-Benzenedialdehyde Request for Quotation

1,2-Phthalic dicarboxaldehyde

CAS: 643-79-8

Molecular Formula: C8H6O2

1,2-Benzenedialdehyde - Names and Identifiers

1,2-Benzenedialdehyde - Physico-chemical Properties

1,2-Benzenedialdehyde - Risk and Safety

1,2-Benzenedialdehyde - Upstream Downstream Industry

1,2-Benzenedialdehyde - Reference

1,2-Benzenedialdehyde - Introduction

1,2-Benzenedialdehyde - Security information

1,2-Benzenedialdehyde - Nature

1,2-Benzenedialdehyde - Uses and synthesis methods

Supplier List

1,2-Benzenedialdehyde