1,2-Bis(4-pyridyl)acetylene

1,2-Bis(4-pyridyl)acetylene - Names and Identifiers

Name	4,4'-ethyne-1,2-diyldipyridine
Synonyms	1,2-Di(pyridin-4-yl) 1,2-bis(4-pyridyl)ethyne 1,2-bis(4-pyridy)acetylene 1,2-di(pyridin-4-yl)ethyne 1,2-Bis(4-pyridyl)acetylene 4,4'-ethyne-1,2-diyldipyridine 4-(2-pyridin-4-ylethynyl)pyridine Pyridine, 4,4'-(1,2-ethynediyl)bis- 4,4-dipyridylacetylene hydrochloride
CAS	73564-69-9
InChI	InChI=1/C12H8N2/c1(11-3-7-13-8-4-11)2-12-5-9-14-10-6-12/h3-10H

1,2-Bis(4-pyridyl)acetylene - Physico-chemical Properties

Molecular Formula	C12H8N2
Molar Mass	180.21
Density	1.18±0.1 g/cm3(Predicted)
Melting Point	114-116 °C
Boling Point	350.9±17.0 °C(Predicted)
Flash Point	155.1°C
Vapor Presure	8.6E-05mmHg at 25°C
pKa	2.97±0.26(Predicted)
Storage Condition	2-8°C
Refractive Index	1.631

1,2-Bis(4-pyridyl)acetylene - Introduction

4,4 '-ethyne-1,2-diyldipyridine, also known as DPPE, is an organic compound. The following is a description of its nature, use, formulation and safety information:

Properties: DPPE is a colorless to light yellow solid with a special aromatic odor. It is stable at room temperature and pressure, insoluble in water, but soluble in many organic solvents. It can be slowly oxidized in air and needs to be stored under anhydrous and nitrogen protection.

Purpose: DPPE has important application value in organic synthesis. It can be used as a catalyst, ligand or reagent in a variety of chemical reactions. Especially in metal-catalyzed reactions, DPPE can form stable complexes with metal complexes for catalytic hydrogenation, hydrogen fixation and asymmetric catalysis.

Preparation method: The preparation method of DPPE can be obtained by reacting pyridine with dibromoacetylene. First, dibromoacetylene is reacted with pyridine in an appropriate solvent to form DPPE, which is then purified by crystallization or column chromatography to obtain the target product.

Safety Information: Appropriate safety measures should be taken when handling DPPE. It can be irritating to the eyes, skin, and respiratory tract, so chemical glasses, gloves, and respiratory protection are required. In addition, ensure that you operate in a well-ventilated laboratory environment and avoid exposure to fire sources or high temperatures. Avoid contact with oxygen, acids, alkalis and other flammable substances during storage and handling to prevent accidents. In all cases, follow the correct laboratory practices and safe operating instructions.

Last Update：2024-04-09 21:01:54