1,2-Didehydro-6ξ,7ξ-epoxy-3β,15,16-trimethoxy-C-homoerythrinan - Names and Identifiers
Name | 3-Epiwilsonine
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Synonyms | 3-Epiwilsonine Alkaloid PC-VII 1,2-Didehydro-6ξ,7ξ-epoxy-3β,15,16-trimethoxy-C-homoerythrinan C-Homoerythrinan, 1,2-didehydro-6,7-epoxy-3,15,16-trimethoxy-, (3beta, 6xi)- (10bR)-1a,2,5,6,11,12-Hexahydro-8,9,12β-trimethoxy-4H-oxireno[3,3a]indolo[7a,1-a][2]benzazepine (1aR,10bR,12R,14aS)-8,9,12-Trimethoxy-1a,2,5,6,11,12-hexahydro-4H-oxireno[3,3a]indolo[7a,1-a][2]benzazepine 4H-Oxireno[3,3a]indolo[7a,1-a][2]benzazepine, 1a,2,5,6,11,12-hexahydro-8,9,12-trimethoxy-, (1aR,10bR,12R,14aS)- 4H-Oxireno[3,3a]indolo[7a,1-a][2]benzazepine,1a,2,5,6,11,12-hexahydro-8,9,12-trimethoxy-, [1aR-(1aa,10bR*,12a)]- (9CI)
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CAS | 39024-15-2
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1,2-Didehydro-6ξ,7ξ-epoxy-3β,15,16-trimethoxy-C-homoerythrinan - Physico-chemical Properties
Molecular Formula | C20H25NO4
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Molar Mass | 343.42 |
Density | 1.27±0.1 g/cm3(Predicted) |
Melting Point | 103-4°C |
Boling Point | 474.8±45.0 °C(Predicted) |
Specific Rotation(α) | +60.7 (c, 0.55 in CHCl3).+75.8 (c, 0.52 in EtOH) |
Solubility | Chloroform, Dichloromethane, Ethyl Acetate, DMSO, Acetone, etc. |
Appearance | Oil |
pKa | 6.07±0.40(Predicted) |
Storage Condition | 2-8℃ |
MDL | MFCD17214790 |
1,2-Didehydro-6ξ,7ξ-epoxy-3β,15,16-trimethoxy-C-homoerythrinan - Introduction
3-Epiwilsonine(3-Epiwilsonine) is a natural alkaloid, belonging to the indole disaccharide compounds. It is isolated from a number of plants, such as the Taiwan three-pointed Cedar (Celastrus hindsii) and the South African three-pointed Cedar (Catharanthus roseus) and so on. Its chemical formula is C16H21NO4. The following is a description of some properties, uses, methods and safety information about 3-Epiwilsonine:
Nature:
-Appearance: 3-Epiwilsonine is a colorless or slightly yellow crystalline solid.
-Solubility: It is soluble in ethanol, dichloromethane and Ether solvents, insoluble in water.
-Chemical properties: It is an alkaline substance, which is prone to alkali-catalyzed decarboxylation.
Use:
-Anti-tumor activity: 3-Epiwilsonine shows anti-tumor activity and has an inhibitory effect on certain cancer cells.
-Drug research: Due to its anti-tumor activity, 3-Epiwilsonine is widely used in drug research and development.
Method:
3-Epiwilsonine can be obtained by extracting from plants such as Taiwan or South Africa. After extraction, the pure product can be obtained by crystallization and purification process.
Safety Information:
-Safety precautions: 3-Epiwilsonine is a chemical substance that needs to be handled and operated properly to avoid inhalation, ingestion or contact with skin and eyes. Wear protective gloves and goggles during use.
-Toxicity: The toxicity and side effects of 3-Epiwilsonine need to be further studied and evaluated, so care should be taken when conducting research and application.
Please note that this information is for reference only. For specific use and application, please consult a professional chemist or related expert.
Last Update:2024-04-09 20:49:11