1,2-dioleoyl-sn-glycero-3-phosphoethanolamine
1,2-dioleoyl-sn-glycero-3-phosphoethanolamine
CAS: 4004-05-1
Molecular Formula: C41H78NO8P
1,2-dioleoyl-sn-glycero-3-phosphoethanolamine - Names and Identifiers
1,2-dioleoyl-sn-glycero-3-phosphoethanolamine - Physico-chemical Properties
| Molecular Formula | C41H78NO8P |
| Molar Mass | 744.05 |
| Density | 1.008±0.06 g/cm3(Predicted) |
| Melting Point | 200°C(lit.) |
| Boling Point | 759.2±70.0 °C(Predicted) |
| Appearance | lyophilized powder |
| Color | White to Light yellow |
| BRN | 1718431 |
| pKa | 1.17±0.50(Predicted) |
| Storage Condition | -20°C |
| In vitro study | In this study, each siRNA is encapsulated in LNP (cationic lipid-A: PEG2000-DMPE: DOPE = 47.8: 5.18: 47.1 molar percent).With the neutral lipid for the LNP is DOPE , LNP exerts knock-down (KD) effecton macrophages and DCs and Liposome-containing DOPE shows fusogenicity.LNP/siRNA significantly suppresses CD45 protein expression at an inhibition rate of 30% on macrophages and DCs but not on monocytes, neutrophils, plasmacytoid DCs, or B cells.LNP has the potential to be an efficient siRNA delivery system not only for murine but also for human macrophages and DCs. |
1,2-dioleoyl-sn-glycero-3-phosphoethanolamine - Risk and Safety
| Hazard Symbols | Xn - Harmful |
| Risk Codes | R22 - Harmful if swallowed R38 - Irritating to the skin R40 - Limited evidence of a carcinogenic effect R48/20/22 - R67 - Vapors may cause drowsiness and dizziness R36/38 - Irritating to eyes and skin. R20 - Harmful by inhalation R63 - Possible risk of harm to the unborn child |
| Safety Description | S36/37 - Wear suitable protective clothing and gloves. S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. |
| UN IDs | UN 1888 6.1/PG 3 |
| WGK Germany | 3 |
| FLUKA BRAND F CODES | 8-10-23 |
| HS Code | 29232000 |
1,2-dioleoyl-sn-glycero-3-phosphoethanolamine - Reference
| Reference Show more | 1. [IF=4.813] Wu Yubo et al."The determination of antibacterial mode for cationic lipopeptides brevibacillins against Salmonella typhimurium by quantum chemistry calculation."Appl Microbiol Biot. 2021 Jul;105(13):5643-5655 |
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Spot supply
Product Name: L-alpha-Phosphatidylethanolamine, Dioleoyl Visit Supplier Webpage Request for quotationCAS: 4004-05-1
Tel: 18301782025
Email: 3008007409@qq.com
Mobile: 18021002903
QQ: 3008007409
Wechat: 18301782025
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