1,3-Dihydro-1-d5-phenyl-2H-indol-2-one

1,3-Dihydro-1-d5-phenyl-2H-indol-2-one - Names and Identifiers

Name	1,3-Dihydro-1-d5-phenyl-2H-indol-2-one
Synonyms	NSC 234518-d5 1-Phenyl-oxindole-d5 (3-Hydroxyretinal-D5) 1-Phenyl-2-indolinone-d5 1,3-DIHYDRO-1-D5-PHENYL-2H-INDOL-2-ONE 1,3-Dihydro-1-d5-phenyl-2H-indol-2-one [2H5]-1,3-Dihydro-1-phenyl-2H-indol-2-one
CAS	1189871-32-6

1,3-Dihydro-1-d5-phenyl-2H-indol-2-one - Physico-chemical Properties

Molecular Formula	C14H11NO
Molar Mass	209.24324
Melting Point	120-122°C
Solubility	Chloroform (Slightly), Ethyl Acetate (Slightly)
Appearance	Solid
Color	Pale Yellow to Pale Beige
Storage Condition	-20°C Freezer

1,3-Dihydro-1-d5-phenyl-2H-indol-2-one - Introduction

1, is also known as 1,3-dihydro -1-heavy hydrophenyl -2H-indole -2 ketone, is an organic compound. It has a 2H-indole ring and a keto group in its structure. The following is a description of some of the properties, uses, preparation and safety information of the compound:

Nature:
-Appearance: Colorless crystalline solid
-Melting Point: about 130-135 ℃ (363-408 K)
-Boiling point: About 348-352 ℃ (621-625 K)
-relative molecular mass: 164.27g/mol
-Solubility: Soluble in organic solvents, insoluble in water

Use:
1, is a commonly used organic synthesis intermediate, which can be used to synthesize compounds containing indole groups. It has certain applications in the field of medicine, and is used as a raw material for drug research and drug synthesis.

Method:
1. It can be prepared by a variety of synthetic methods. One of the common methods is:
Benzaldehyde reacts with O-aminoacetophenone under acidic conditions to generate 1-benzyl -1,2,3, 4-tetrahydro-β-indolone. This compound is then converted to 1, Ni by a dehydrogenation reaction.

Safety Information:
1. It is generally considered to be a relatively safe compound, but some safe operations should be paid attention to when handling and storing:
-Avoid inhaling its dust or generating its vapor, and operate in a well-ventilated place.
-Avoid skin contact and wear protective gloves and clothing.
-If you touch your eyes or skin externally, rinse immediately with plenty of water.
-If necessary, follow appropriate laboratory safety guidelines and recommendations in operation. The purchase and use of the compound should comply with the relevant laws and regulations.

Please note that any chemical needs to be handled and used properly, and proper laboratory safety management practices should be followed.

Last Update：2024-04-09 15:18:06