Name | BHPI |
Synonyms | BHPI CS-2134 1,3-Dihydro-3,3-bis(4-hydroxyphenyl)-7-methyl-2H-indol-2-one 2H-Indol-2-one, 1,3-dihydro-3,3-bis(4-hydroxyphenyl)-7-methyl- |
CAS | 56632-39-4 |
Molecular Formula | C21H17NO3 |
Molar Mass | 331.36 |
Density | 1.320±0.06 g/cm3(Predicted) |
Melting Point | 272-274 °C |
Boling Point | 557.7±50.0 °C(Predicted) |
Solubility | DMSO: ≥150 mg/mL |
pKa | 9.43±0.30(Predicted) |
Storage Condition | -20℃ |
1mg | 5mg | 10mg | |
---|---|---|---|
1 mM | 3.018 ml | 15.089 ml | 30.178 ml |
5 mM | 0.604 ml | 3.018 ml | 6.036 ml |
10 mM | 0.302 ml | 1.509 ml | 3.018 ml |
5 mM | 0.06 ml | 0.302 ml | 0.604 ml |
biological activity | BHPI is an inhibitor of the nuclear receptor ER_alpha, it can inhibit cancer cell protein synthesis and activate unfolded protein response (UPR). |