1,4-Bis(Hydroxymethyl)-2,3,5,6-Tetramethylbenzene

1,4-Bis(Hydroxymethyl)-2,3,5,6-Tetramethylbenzene - Names and Identifiers

Name	1,4-Bis(Hydroxymethyl)-2,3,5,6-Tetramethylbenzene
Synonyms	BIS(HYDROXYMETHYL)DURENE 3,6-BIS(HYDROXYMETHYL)DURENE hexamethylbenzene-alpha1,alpha4-diol 2,3,5,6-TETRAMETHYL-P-XYLENE-ALPHA,ALPHA'-DIOL 2,3,5,6-tetramethyl-para-xylene-alpha,alpha'-diol 1,4-Bis(Hydroxymethyl)-2,3,5,6-Tetramethylbenzene 1,4-BIS(HYDROXYMETHYL)-2,3,5,6-TETRAMETHYLBENZENE 1,4-Bis(hydroxymethyl)-2,3,5,6-tetramethylbenzene2,3,5,6-Tetramethyl-p-xylene-alpha,alpha'-diol
CAS	7522-62-5
EINECS	231-382-9

1,4-Bis(Hydroxymethyl)-2,3,5,6-Tetramethylbenzene - Physico-chemical Properties

Molecular Formula	C12H18O2
Molar Mass	194.27
Melting Point	246-248°C(lit.)
Solubility	within almost transparency in hot Pyridine
Appearance	powder to crystal
Color	White to Light yellow to Light orange
Storage Condition	2-8℃
MDL	MFCD00004623

1,4-Bis(Hydroxymethyl)-2,3,5,6-Tetramethylbenzene - Risk and Safety

WGK Germany

1,4-Bis(Hydroxymethyl)-2,3,5,6-Tetramethylbenzene - Introduction

1,4-bis (Hydroxymethyl)-2,3, 5,6-tetramethylbenzene is an organic compound with the chemical formula C16H22O2. The following is a description of its nature, use, preparation and safety information:

Nature:
-Appearance: 1,4-bis (Hydroxymethyl)-2,3,5,6-tetramethylbenzene as a colorless or light yellow solid.
-Solubility: Soluble in organic solvents such as ethanol, dichloromethane, acetone, etc.
-Melting Point: about 180~182 ℃.

Use:
1,4-bis (Hydroxymethyl)-2,3, 5,6-tetramethylbenzene is an important organic synthesis intermediate and has some applications:
-It can be used to produce ring-embedded compounds in the synthesis of acetals condensed with aldehydes.
-In the field of medicine, it can be used to synthesize intermediates of some drugs, such as anticancer drug Capecitabine (Capecitabine).
-It can also be used as an additive in the manufacturing process of cosmetics and personal care products.

Method:
1,4-bis (Hydroxymethyl)-2,3, 5,6-tetramethylbenzene is generally prepared by the following steps:
1. First, 2,3,5,6-tetramethylbenzene is synthesized by an appropriate method.
2. Subsequently, 2,3,5,6-tetramethylbenzene is reacted with formaldehyde to produce 1,4-bis (Hydroxymethyl)-2,3,5,6-tetramethylbenzene after a series of reaction steps.

Safety Information:
Based on currently available information, 1,4-bis (Hydroxymethyl)-2,3,5,6-tetramethylbenzene is generally considered to be relatively safe under normal conditions of use. However, when handling and using, you still need to pay attention to the following safety measures:
-Avoid contact with skin and eyes.
-Good ventilation must be maintained during operation.
-Avoid inhaling gases, vapors, fumes and dust.
-Use appropriate personal protective equipment, such as gloves, protective glasses and laboratory coats.

Please note that the information provided here is for reference only. Relevant scientific and technical literature and safety manuals are also required for specific use.

Last Update：2024-04-09 21:01:54