1,4-Butanediylbiscyanide

1,4-Butanediylbiscyanide - Names and Identifiers

Name	1,4-Dicyanobutane
Synonyms	Adiponitrile hexanedinitrile 1,4-Dicyanobutane Esmolol Impurity 5 HCl 1,4-Butanediylbiscyanide Butane-1,4-dicarbonitrile Tetramethylene Dicyanide Adiponitrile
CAS	111-69-3
EINECS	203-896-3

1,4-Butanediylbiscyanide - Physico-chemical Properties

Molecular Formula	C6H8N2
Molar Mass	108.14
Density	0.951 g/mL at 25 °C (lit.)
Melting Point	1-3 °C (lit.)
Boling Point	295 °C (lit.)
Flash Point	163 °C
Water Solubility	90 g/L (20 ºC)
Solubility	50g/l
Vapor Presure	0.01 mm Hg ( 40 °C)
Vapor Density	3.7 (vs air)
Appearance	Liquid
Specific Gravity	0.951
Color	Clear colorless to slightly yellow
Exposure Limit	TLV-TWA 18 mg/m3 (4 ppm) (NIOSH).
BRN	1740005
Storage Condition	Store below +30°C.
Explosive Limit	7-14%(V)
Refractive Index	n20/D 1.438(lit.)
Physical and Chemical Properties	Colorless transparent oily liquid, with slight bitter taste. boiling point 295 ℃ freezing point 1 ℃ relative density 0.9650 refractive index 1.4380 flash point 159 ℃ soluble in methanol, ethanol, chloroform. Insoluble in water, cyclohexane, ether, carbon disulfide and carbon tetrachloride.
Use	Used as chromatographic stationary liquid

1,4-Butanediylbiscyanide - Risk and Safety

Hazard Symbols	T - Toxic
Risk Codes	R25 - Toxic if swallowed R36/37/38 - Irritating to eyes, respiratory system and skin. R36/38 - Irritating to eyes and skin. R23/25 - Toxic by inhalation and if swallowed.
Safety Description	S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. S36 - Wear suitable protective clothing. S45 - In case of accident or if you feel unwell, seek medical advice immediately (show the label whenever possible.) S39 - Wear eye / face protection.
UN IDs	UN 2205 6.1/PG 3
WGK Germany	1
RTECS	AV2625000
TSCA	Yes
HS Code	29269090
Hazard Class	6.1
Packing Group	III
Toxicity	LD50 orally in Rabbit: 138 mg/kg LD50 dermal Rabbit 2134 mg/kg

1,4-Butanediylbiscyanide - Upstream Downstream Industry

Raw Materials

Adipic acid

1,4-Butanediylbiscyanide - Nature

Open Data Verified Data

colorless transparent oily liquid, flammable. Slightly bitter taste. Soluble in methanol, ethanol, chloroform. Insoluble in water, cyclohexane, ether, carbon disulfide and carbon tetrachloride. The relative density was 0.9650. Boiling point 295 °c. Freezing point 1 ℃. Flash point (closed cup) 159 °c. Refractive index 4380. Adipic acid is generated during hydrolysis and hexamethylene diamine is generated during reduction.

Last Update：2024-01-02 23:10:35

1,4-Butanediylbiscyanide - Preparation Method

Open Data Verified Data

Amidation of adipic acid the reaction of adipic acid and excess ammonia in the presence of the catalyst phosphoric acid or its salts or esters is carried out at a temperature of 270~290 °c to produce diammonium adipate, then, the crude adiponitrile is produced by heating and dehydration, and the product is obtained by distillation.
acrylonitrile electrolytic dimerization method acrylonitrile solution electrolysis the cathode region was separated from the anode region by a cation exchange membrane, the anode liquid was diluted sulfuric acid, and the cathode liquid was an acrylonitrile solution. Its concentration is 25% ~ 40%. The pH value of the Catholyte is maintained at 7-9.5, and acrylonitrile is Bis-polymerized into adiponitrile by electrolytic reduction, and the finished product is obtained by rectification.

Last Update：2022-01-01 10:37:03

1,4-Butanediylbiscyanide - Use

Open Data Verified Data

This product is used for the preparation of polyamide fiber intermediate hexamethylene diamine, rubber accelerator and rust inhibitor. Also used as detergent additives, acrylonitrile, methyl acrylonitrile and methyl methacrylate Ternary Polymer spinning solvent, polyvinyl chloride fiber wet spinning and dry spinning solvent, polyamide colorant, fabric bleaching agent, and used as acetate, plasticizers for propionate, butyrate and mixed esters.

Last Update：2022-01-01 10:37:03

1,4-Butanediylbiscyanide - Safety

Open Data Verified Data

This product is toxic, through oral inhalation or skin absorption can cause poisoning. The LD50 of mice was 38. 8 mg/kg, and the LD50 of rats was 154. 8 mg/kg. Effect on the skin, to the guinea pig with this product to wipe the skin, after 3, 4 to 16 times after the application, some animals died. The maximum allowable concentration in air is 15~20mg/m3. Human chronic poisoning can cause leukopenia and mononuclear leukocytosis. If you inhale adiponitrile vapor or accidentally swallow a few milliliters of adiponitrile, it can cause Nausea, Vomit, mucous membrane irritation and dizziness. The victim should be immediately sent to hospital for treatment, injection of sodium thiosulfate and other drugs, to restore normal cardiopulmonary organ activity. In case of Dyspnea, the pulse is accelerated, the consciousness is blurred, the blood pressure is obviously lowered, the limb facial tissue numbness or convulsion, must be oxygen. If contact with the eyes, the application of a large number of water for 20 minutes, and then sent to the hospital for treatment. If in contact with the skin, wash with soap and water. The production workshop should be well ventilated and the equipment should be closed. The operator should wear protective gear. See acrylonitrile for Protection Measure.
This product is packaged in an iron drum, 200kg per barrel, and is stored and transported according to the provisions of flammable drugs.

Last Update：2022-01-01 10:37:04

1,4-Butanediylbiscyanide - Reference Information

freezing point	1 ℃
NIST chemical information	information provided by: webbook.nist.gov (external link)
EPA chemical substance information	information provided by: ofmpeb.epa.gov (external link)
Introduction	adiponitrile is an organic compound having the molecular formula (CH2)4(CN)2. It is a viscous, colorless liquid that is an important precursor of the polymer nylon 66. In, its production capacity can reach 0.1 billion.
Application	The dinitrile is mainly used for the production of polyamide fiber intermediate diamine, rubber accelerator and rust inhibitor, also used as detergent additives, acrylonitrile, methyl acrylonitrile and methyl methacrylate Ternary Polymer spinning solvent, polyvinyl chloride fiber wet spinning and dry spinning solvent, polyamide colorant, fabric bleaching agent, acetate, propionate, butyric acid ester and mixed Ester plasticizer; And as an extractant for aromatic extraction, etc. used as chromatographic stationary liquid
production method	at present, the main method for the industrial production of dinitriles is the ammoniation of adipic acid, butadiene method and acrylonitrile dimerization method, which has been the earliest industrialization of amidation, technology is relatively mature, the largest application. 1. Amidation of adipic acid adipic acid and excess ammonia in the presence of the catalyst phosphoric acid or its salts or esters, at a temperature of 270-290 ° C. Reaction, the formation of diammonium adipate, and then heating dehydration, crude adiponitrile, the product was obtained by distillation. Raw material consumption quota: Adipic acid 1606kg/t, liquid ammonia 370kg/t, sodium hydroxide 36kg/t. The butadiene method is also divided into chlorination and direct hydrocyanation. 3. Acrylonitrile electrolytic dimerization method the electrolyte is p-toluene tetraethylamine sulfonate, temperature 50-60 ℃, has two nitrile yield 92-95%. The hydrogenation dimerization of acrylonitrile can also be carried out by using a gas phase catalytic hydrogenation method using ruthenium catalyst at 200-300 ° C. And 0.1-0.3MPa. Raw material consumption quota: acrylonitrile 1100kg/t, sulfuric acid 80kg/t.
category	toxic substances
toxicity grade	high toxicity
Acute toxicity	oral-rat LD50:155 mg/kg; Oral-mouse LD50:172 mg/kg
flammability hazard characteristics	open flame flammability; High thermal decomposition; Interaction with oxidant; combustion releases toxic nitrogen oxides and cyanide fumes
storage and transportation characteristics	The warehouse is ventilated and dried at low temperature, separate storage of food additives
extinguishing agent	dry powder, foam, carbon dioxide, sand.
Occupational Standard	TWA 4 PPM; Tel 10 mg/m3
spontaneous combustion temperature	460°C
toxic substance data	information provided by: pubchem.ncbi.nlm.nih.gov (external link)

Last Update：2024-04-10 22:29:15

Hangzhou Verychem Science And Technology Co.Ltd

1,4-Butanediylbiscyanide

1,4-Dicyanobutane

CAS: 111-69-3

Molecular Formula: C6H8N2

1,4-Butanediylbiscyanide - Names and Identifiers

1,4-Butanediylbiscyanide - Physico-chemical Properties

1,4-Butanediylbiscyanide - Risk and Safety