Name | 1,6-naphthyridin-5(6H)-one |
Synonyms | 1,6-naphthyridin-5-ol 1,6-Naphthyridin-5(6H) 1,6-Naphthyridin-5-one 6H-1,6-naphthyridin-5-one 1,6-Naphthyridin-5(6H)-one 1,6-naphthyridin-5(6H)-one 1,6-NAPHTHYRIDIN-5(6H)-ONE 5-Hydroxy-1,6-naphthyridine 5,6-dihydro-1,6-naphthyridin-5-one |
CAS | 23616-31-1 |
InChI | InChI=1/C8H6N2O/c11-8-6-2-1-4-9-7(6)3-5-10-8/h1-5H,(H,10,11) |
Molecular Formula | C8H6N2O |
Molar Mass | 146.15 |
Density | 1.267±0.06 g/cm3(Predicted) |
Melting Point | 239-241°C |
Boling Point | 425.6±45.0 °C(Predicted) |
Flash Point | 211.192°C |
Vapor Presure | 0mmHg at 25°C |
pKa | 11.18±0.20(Predicted) |
Storage Condition | Sealed in dry,Room Temperature |
Refractive Index | 1.603 |
Hazard Class | IRRITANT |
Introduction | new compound 1, 6-naphthopyridin-5 (6H)-one, its molecular structure contains pyridine naphthalene ring, and contains active N-H, it can be further derived into other functional groups. The naphthopyridine ring is present as an active functional group in a biological enzyme such as an anti-nucleotide acceptor agent, a glycogen synthase inhibitor molecule. Therefore, 1, 6-naphthopyridin-5 (6H)-one can be used as a potential active functional group and will be gradually applied to the synthesis of new drugs. |
Use | 1, 6-naphthopyridin-5 (6h)-one is a pyridine heterocyclic derivative, it can be used as a pharmaceutical intermediate, and used in pharmaceutical experimental research and pharmaceutical synthesis. |
synthesis method | a route map for the synthesis of 1, 6-naphthopyridin-5 (6H)-one is as follows: |