1-(((2S,3S,4S)-3-ethyl-4-fluoro-5-oxopyrrolidin-2-yl)methoxy)-7-methoxyisoquinoline-6-carboxamide
PF06650833
CAS: 1817626-54-2
Molecular Formula: C18H20FN3O4
1-(((2S,3S,4S)-3-ethyl-4-fluoro-5-oxopyrrolidin-2-yl)methoxy)-7-methoxyisoquinoline-6-carboxamide - Names and Identifiers
1-(((2S,3S,4S)-3-ethyl-4-fluoro-5-oxopyrrolidin-2-yl)methoxy)-7-methoxyisoquinoline-6-carboxamide - Physico-chemical Properties
| Molecular Formula | C18H20FN3O4 |
| Molar Mass | 361.37 |
| Density | 1.34±0.1 g/cm3(Predicted) |
| Boling Point | 621.0±55.0 °C(Predicted) |
| Solubility | DMSO: ≥ 33 mg/mL |
| Appearance | powder |
| Color | white to beige |
| pKa | 13.44±0.70(Predicted) |
| Storage Condition | room temp |
1-(((2S,3S,4S)-3-ethyl-4-fluoro-5-oxopyrrolidin-2-yl)methoxy)-7-methoxyisoquinoline-6-carboxamide - Preparation solution concentration reference
| 1mg | 5mg | 10mg | |
|---|---|---|---|
| 1 mM | 2.767 ml | 13.836 ml | 27.673 ml |
| 5 mM | 0.553 ml | 2.767 ml | 5.535 ml |
| 10 mM | 0.277 ml | 1.384 ml | 2.767 ml |
| 5 mM | 0.055 ml | 0.277 ml | 0.553 ml |
Last Update：2024-01-02 23:10:35
1-(((2S,3S,4S)-3-ethyl-4-fluoro-5-oxopyrrolidin-2-yl)methoxy)-7-methoxyisoquinoline-6-carboxamide - Reference Information
| biological activity | PF-06650833 is an effective IRAK4 selective inhibitor with IC50 of 0.2 nM. |
| target | TargetValue IRAK4 (Cell-free assay) 0.2 nM |
| Target | Value |
| IRAK4 (Cell-free assay) | 0.2 nM |
Last Update：2024-04-09 21:31:57
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Product Name: Zimlovisertib Visit Supplier Webpage Request for quotationCAS: 1817626-54-2
Tel: 0714-3999186
Email: 2853786052@qq.com
Mobile: 86+15671228036
QQ: 2853786052
Wechat: 15671228036
Spot supply
Product Name: PF06650833 Visit Supplier Webpage Request for quotationCAS: 1817626-54-2
Tel: 18301782025
Email: 3008007409@qq.com
Mobile: 18021002903
QQ: 3008007409
Wechat: 18301782025
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