1-(1-Phenyl-2-acetyl-2-methylhydrazino)-2-(dimethylamino)-1,2-ethanedione
Dioxoaminopyrine
CAS: 519-65-3
Molecular Formula: C13H17N3O3
1-(1-Phenyl-2-acetyl-2-methylhydrazino)-2-(dimethylamino)-1,2-ethanedione - Names and Identifiers
| Name | Dioxoaminopyrine |
| Synonyms | DioxyaMinopyrine Dioxoaminopyrine 1-Acetyl-1,5,5-triMethyl-2-phenylseMioxaMazide α-(DiMethylaMidooxalyl)-β,β-Methylacetylphenylhydrazine N'-acetyl-2-(dimethylamino)-N'-methyl-2-oxo-N-phenylacetohydrazide N,N-Dimethyl-2-oxo-2-(1-phenyl-2-acetyl-2-methylhydrazino)acetamide 2-(DiMethylaMino)-2-oxo-acetic Acid 2-Acetyl-2-Methyl-1-phenylhydrazide 1-(1-Phenyl-2-acetyl-2-methylhydrazino)-2-(dimethylamino)-1,2-ethanedione |
| CAS | 519-65-3 |
| EINECS | 2082745 |
1-(1-Phenyl-2-acetyl-2-methylhydrazino)-2-(dimethylamino)-1,2-ethanedione - Physico-chemical Properties
| Molecular Formula | C13H17N3O3 |
| Molar Mass | 263.29 |
| Density | 1.1651 (rough estimate) |
| Melting Point | 105.5° (softens at 96°) |
| Boling Point | bp2 194-201° |
| pKa | -0.84±0.50(Predicted) |
| Storage Condition | 2-8°C |
| Refractive Index | 1.5700 (estimate) |
1-(1-Phenyl-2-acetyl-2-methylhydrazino)-2-(dimethylamino)-1,2-ethanedione - Introduction
Dioxoaminopyrine (aminopyridine dioxide) is a drug, also known as aminopyridoxone (Aminopyrine). It is a white crystalline solid, insoluble in water at room temperature, but soluble in hot water and some organic solvents.
Aminopyridoxone is commonly used as an antipyretic analgesic. It has anti-inflammatory, analgesic and antipyretic properties and is commonly used to relieve headaches, arthritis and other pain-related symptoms. In addition, it can also be used to measure renal function and blood flow, as well as to evaluate liver detoxification.
The method for preparing aminopyridoxone is usually by reacting pyridine and epoxyaminopropane to form an epoxy compound of aminopyridine, followed by an oxidation reaction to form aminopyridoxone. The specific synthesis steps require certain chemical experimental conditions and equipment, and need to be carried out in an experienced chemical laboratory.
Regarding safety information, aminopyridoxone is generally safe when used and at the correct dose, but long-term or high-dose use may cause some adverse reactions. These adverse reactions may include allergic reactions, gastrointestinal reactions, liver damage and hematopoietic suppression. In addition, aminopyridoxone may interact with other drugs, so it is necessary to pay attention to communication and guidance with doctors or pharmacists when using it.
Aminopyridoxone is commonly used as an antipyretic analgesic. It has anti-inflammatory, analgesic and antipyretic properties and is commonly used to relieve headaches, arthritis and other pain-related symptoms. In addition, it can also be used to measure renal function and blood flow, as well as to evaluate liver detoxification.
The method for preparing aminopyridoxone is usually by reacting pyridine and epoxyaminopropane to form an epoxy compound of aminopyridine, followed by an oxidation reaction to form aminopyridoxone. The specific synthesis steps require certain chemical experimental conditions and equipment, and need to be carried out in an experienced chemical laboratory.
Regarding safety information, aminopyridoxone is generally safe when used and at the correct dose, but long-term or high-dose use may cause some adverse reactions. These adverse reactions may include allergic reactions, gastrointestinal reactions, liver damage and hematopoietic suppression. In addition, aminopyridoxone may interact with other drugs, so it is necessary to pay attention to communication and guidance with doctors or pharmacists when using it.
Last Update：2024-04-09 20:52:54
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