1-(1-methylindol-3-yl)ethanone

1-(1-methylindol-3-yl)ethanone - Names and Identifiers

Name	1-(1-METHYL-1H-INDOL-3-YL)-1-ETHANONE
Synonyms	N-Methyl-3-acetylindole 3-Acetyl-1-methylindole 1-Methyl-3-acetylindole 1-(1-methylindol-3-yl)ethanone 1-(1-methyl-3-indolyl)ethanone 1-(1-METHYL-1H-INDOL-3-YL)-1-ETHANONE 1-(1-methyl-1H-indol-3-yl)ethan-1-one 1-(1-Methyl-1H-indole-3-yl)-1-ethanone
CAS	19012-02-3

1-(1-methylindol-3-yl)ethanone - Physico-chemical Properties

Molecular Formula	C11H11NO
Molar Mass	173.21
Density	1.09
Melting Point	108-109℃
Boling Point	130-140 °C(Press: 0.01 Torr)
Storage Condition	Sealed in dry,Room Temperature
Sensitive	Irritant
MDL	MFCD00540232

1-(1-methylindol-3-yl)ethanone - Risk and Safety

Risk Codes	36 - Irritating to the eyes
Safety Description	26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.
Hazard Class	IRRITANT

1-(1-methylindol-3-yl)ethanone - Upstream Downstream Industry

Raw Materials

3-ACETYL-1-(PHENYLSULFONYL)INDOLE
3-(CYANOACETYL)-1-METHYLINDOLE
3-Acetylindole
1-Methylindole
3-METHYL-2,4-PENTANEDIONE
METHYL FLUORIDE
Methanol
Acetyl chloride
Indole
Acetonitrile
Pyruvic acid

1-(1-methylindol-3-yl)ethanone - Introduction

1-(1-METHYL-1H-INDOL-3-YL)-1-ETHANONE, chemical formula C12H13NO, is an organic compound. The following is a description of the nature, use, preparation and safety information of the substance:

Nature:
1-(1-METHYL-1H-INDOL-3-YL)-1-ETHANONE is a solid with pale yellow to orange crystals. It is stable at room temperature and soluble in organic solvents such as dimethyl sulfoxide and alcohols. The melting point of this compound is about 82-84°C.

Use:
1-(1-METHYL-1H-INDOL-3-YL)-1-ETHANONE has certain applications in the field of medicine. It acts as an interesting solubility enhancer that can be used to improve the bioavailability of drugs. In addition, it can also be used in the synthesis of other organic compounds, such as fluorescent markers.

Method:
There are many synthetic methods of 1-(1-METHYL-1H-INDOL-3-YL)-1-ETHANONE, one of the main methods is obtained by the reaction of acetylacetone and indole. In the reaction, acetylacetone reacts with indole under alkaline conditions to produce 1-(1-METHYL-1H-INDOL-3-YL)-1-ETHANONE.

Safety Information:
There are relatively few specific reports of toxicity and safety information on 1-(1-METHYL-1H-INDOL-3-YL)-1-ETHANONE. Under normal circumstances, the necessary personal protective measures, such as gloves and eye protection, should be taken when handling this compound. In any chemical experiment, you should follow the correct laboratory operating procedures and follow the relevant regulations and safety measures. If necessary, refer to the safety data form provided by the supplier for more safety information.

Last Update：2024-04-09 21:54:55