1-(2,4-DICHLOROPHENYL)-2-(1H-IMIDAZOL-1-YL)ETHANONE
2'-(1H-Imidazole-1-yl)-2,4-dichloroacetophenone
CAS: 46503-52-0
Molecular Formula: C11H8Cl2N2O
1-(2,4-DICHLOROPHENYL)-2-(1H-IMIDAZOL-1-YL)ETHANONE - Names and Identifiers
| Name | 2'-(1H-Imidazole-1-yl)-2,4-dichloroacetophenone |
| Synonyms | AURORA KA-666 2',4'-DICHLORO-2-IMIDAZOLYLACETOPHENONE 2,4'-Dichloro Phenyl-2-Imidazole-1-Ethanone 2'-(1H-imidazl-1-yl)-2,4-dichloroacetophenone 2'-(1H-Imidazole-1yl)-2,4-Dichloroacetophenone 2',4'-Dichloro-2-(1H-imidazol-1-yl)acetophenone 2'-(1H-IMIDAZOLE-1-YL)-2,4-DICHLOROACETOPHENONE 1-(2,4-DICHLOROPHENYL)-2-IMIDAZOL-1-YL-ETHANONE 2'-(1H-Imidazole-1-yl)-2,4-dichloroacetophenone 2'-(1H-Imidazole-1-Yl)-2,4-Dichloro Acetophenone 1-(2,4-Dichloro-phenyl)-2-imidazol-1-yl-ethanone 1-(2,4-dichlorophenyl)-2-(1H-imidazol-2-yl)ethanone 1-(2,4-dichlorophenyl)-2-(1H-imidazol-1-yl)ethanone 1-(2,4-DICHLOROPHENYL)-2-(1H-IMIDAZOL-1-YL)ETHANONE 1-(2,4-Dichlorophenyl)-2-(1h-imidazole-1-yl) ethanone 1-(2,4-DICHLOROPHENYL)-2-(1H-IMIDAZOLE-1-YL) ETHANONE |
| CAS | 46503-52-0 |
| EINECS | 256-273-3 |
| InChI | InChI=1/C11H8Cl2N2O/c12-7-1-2-8(9(13)5-7)10(16)6-11-14-3-4-15-11/h1-5H,6H2,(H,14,15) |
1-(2,4-DICHLOROPHENYL)-2-(1H-IMIDAZOL-1-YL)ETHANONE - Physico-chemical Properties
| Molecular Formula | C11H8Cl2N2O |
| Molar Mass | 255.1 |
| Density | 1.38±0.1 g/cm3(Predicted) |
| Melting Point | 76-78 °C(Solv: ethyl ether (60-29-7)) |
| Boling Point | 441.1±35.0 °C(Predicted) |
| Flash Point | 244.305°C |
| Vapor Presure | 0mmHg at 25°C |
| pKa | 5.97±0.10(Predicted) |
| Refractive Index | 1.631 |
1-(2,4-DICHLOROPHENYL)-2-(1H-IMIDAZOL-1-YL)ETHANONE - Introduction
2 '-(1H-Imidazole-1-yl)-2,4-dichloroacetophenone is an organic compound with the chemical formula C11H8Cl2N2O. The following is a detailed description of its nature, use, formulation and safety information:
Nature:
-Appearance: White crystalline solid
-melting point: 105-107 ℃
-Boiling point: 385.6 ℃
-Solubility: Soluble in most organic solvents
Use:
- 2 '-(1H-Imidazole-1-yl)-2,4-dichloroacetophenone is an important organic synthesis intermediate, which is widely used in the synthesis of biologically active compounds in organic synthesis.
-It is commonly used in the preparation of organic photosensitive materials, pharmaceutical intermediates and pesticides and other fields.
-In the pharmaceutical field, it is used as an intermediate for antibacterial drugs and anti-cancer drugs.
Preparation Method:
The preparation of -2 '-(1H-Imidazole-1-yl)-2,4-dichloroacetophenone generally uses chemical synthesis methods.
-The specific step can be achieved by introducing a base catalyst in the reaction of 1H-imidazole and 2,4-dichloroacetophenone.
Safety Information:
- 2 '-(1H-Imidazole-1-yl)-2,4-dichloroacetophenone has no apparent hazard under normal conditions of use.
-However, when handling, attention should still be paid to its irritation to the eyes, skin and respiratory system.
-In the operation, the need to take appropriate protective measures, such as wearing protective glasses, gloves and masks, and provide good ventilation conditions.
Nature:
-Appearance: White crystalline solid
-melting point: 105-107 ℃
-Boiling point: 385.6 ℃
-Solubility: Soluble in most organic solvents
Use:
- 2 '-(1H-Imidazole-1-yl)-2,4-dichloroacetophenone is an important organic synthesis intermediate, which is widely used in the synthesis of biologically active compounds in organic synthesis.
-It is commonly used in the preparation of organic photosensitive materials, pharmaceutical intermediates and pesticides and other fields.
-In the pharmaceutical field, it is used as an intermediate for antibacterial drugs and anti-cancer drugs.
Preparation Method:
The preparation of -2 '-(1H-Imidazole-1-yl)-2,4-dichloroacetophenone generally uses chemical synthesis methods.
-The specific step can be achieved by introducing a base catalyst in the reaction of 1H-imidazole and 2,4-dichloroacetophenone.
Safety Information:
- 2 '-(1H-Imidazole-1-yl)-2,4-dichloroacetophenone has no apparent hazard under normal conditions of use.
-However, when handling, attention should still be paid to its irritation to the eyes, skin and respiratory system.
-In the operation, the need to take appropriate protective measures, such as wearing protective glasses, gloves and masks, and provide good ventilation conditions.
Last Update：2024-04-09 02:00:46
