1-(2,5-dihydroxy-3,4,6-trimethoxy-phenyl)-3-phenyl-prop-2-en-1-one - Names and Identifiers
Name | Pedicin
|
Synonyms | Pedicin PEDICIN 2',5'-DIHYDROXY-3',4',6'-TRIMETHOXYCHALCONE 3',6'-DIHYDROXY-2',4',5'-TRIMETHOXYCHALCONE DIHYDROXY-2',4',5'-TRIMETHOXYCHALCONE, 3',6' (E)-2',5'-Dihydroxy-3',4',6'-trimethoxychalcone 1-(2,5-dihydroxy-3,4,6-trimethoxyphenyl)-3-phenylprop-2-en-1-one 1-(2,5-dihydroxy-3,4,6-trimethoxy-phenyl)-3-phenyl-prop-2-en-1-one 2-Propen-1-one, 1-(2,5-dihydroxy-3,4,6-trimethoxyphenyl)-3-phenyl-, (2E)-
|
CAS | 521-51-7
|
1-(2,5-dihydroxy-3,4,6-trimethoxy-phenyl)-3-phenyl-prop-2-en-1-one - Physico-chemical Properties
Molecular Formula | C18H18O6
|
Molar Mass | 330.33 |
Density | 1.276±0.06 g/cm3(Predicted) |
Melting Point | 145 °C |
Boling Point | 583.0±50.0 °C(Predicted) |
Appearance | Orange red |
pKa | 7.55±0.50(Predicted) |
Storage Condition | 2-8℃ |
1-(2,5-dihydroxy-3,4,6-trimethoxy-phenyl)-3-phenyl-prop-2-en-1-one - Introduction
Pedicin(Pedicin) is a compound that has the following properties:
1. Appearance: white solid powder.
2. Solubility: soluble in water and organic solvents, such as ethanol and dimethyl sulfoxide.
3. Chemical structure: It is a compound derived from Chalone, with two hydroxyl groups and three methoxy substituents.
4. Melting Point: about 200-205 ° C.
The main uses of Pedicin are as follows:
1. Antibacterial activity: Pedicin has antibacterial activity and has bactericidal effect on some bacteria and fungi.
Inhibition of biofilm formation: It can inhibit the formation of bacterial and fungal biofilm, and has a certain effect on the prevention and treatment of biofilm-related infections.
3. Drug research: as a compound, Pedicin is commonly used in the field of pharmaceutical research and new drug development.
The method of preparing Pedicin mainly includes the following steps:
1. An appropriate amount of chalcone is reacted with 2-hydroxy ethanol to form a chalcone -2-hydroxy ethanol adduct.
2. The chalcone -2-hydroxy ethanol adduct reacts with methyl copper bromide to generate 2 '-bromo -3',4 ',6'-trimethoxy chalcone.
3. Reacting 2 '-bromo -3',4 ',6'-trimethoxychalcone with sodium sulfite to generate Pedicin.
Note the following safety information when using and handling Pedicin:
1. Because Pedicin has a certain toxicity, you should wear appropriate protective equipment, such as gloves and goggles.
2. Avoid contact with skin and inhalation of dust or gas to avoid allergy or irritation.
3. When used under experimental conditions, good ventilation should be maintained and contact with oxidants or flammable materials should be avoided.
4. In case of misuse or contact, seek medical attention immediately and carry the safety data sheet of the substance.
Last Update:2024-04-09 21:04:16