1-(2,6-difluorophenyl)cyclopropane-1-carbonitrile - Names and Identifiers
1-(2,6-difluorophenyl)cyclopropane-1-carbonitrile - Physico-chemical Properties
| Molecular Formula | C10H7F2N
|
| Molar Mass | 179.17 |
1-(2,6-difluorophenyl)cyclopropane-1-carbonitrile - Introduction
1-(2,6-difluorophenyl)cyclopropane-1-carbonitrile is an organic compound. Its chemical formula is C10H7F2N and its molecular weight is 179.17. The following is an introduction to its nature, use, preparation and safety information:
Nature:
-Appearance: Colorless to light yellow solid
-Melting point: 61-63 ° C
-Boiling point: 290-292 ° C
-Density: 1.313g/cm³
-insoluble in water, soluble in common organic solvents such as methanol, ethanol and dichloromethane.
Use:
- 1-(2,6-difluorophenyl)cyclopropane-1-carbonitrile is widely used in organic synthesis.
-It is used as an intermediate in drug synthesis, especially for the synthesis of anti-cancer and antiviral drugs.
-It can also be used as a research reagent in Materials Chemistry.
Method:
- 1-(2,6-difluorophenyl)cyclopropane-1-carbonitrile can be prepared by cyanation of acetophenone.
-The specific method is to react acetophenone and sodium cyanide in a dichloromethane solvent, and then perform acidic hydrolysis to obtain the target product.
Safety Information:
- 1-(2,6-difluorophenyl)cyclopropane-1-carbonitrile has no reported risk under normal conditions of use.
-However, as an organic compound, it is still necessary to comply with the safety procedures of the organic synthesis laboratory, including wearing appropriate personal protective equipment (such as gloves, goggles, etc.).
-When storing, it should be stored in a sealed container, stored in a cool, dry place, away from fire and oxidizing agents.
Last Update：2024-04-09 02:00:51