1-(2-Azidoethoxy)-2-(2-bromoethoxy)ethane
Bromo-PEG2-azide
CAS: 530151-56-5
Molecular Formula: C6H12BrN3O2
1-(2-Azidoethoxy)-2-(2-bromoethoxy)ethane - Names and Identifiers
| Name | Bromo-PEG2-azide |
| Synonyms | Br-PEG2-N3 N3-PEG2-Br Azido-PEG2-Br Bromo-PEG2-azide N3-PEG2-CH2CH2Br Azido-PEG3-bromide Bromo-PEG2-C2-azide 1-(2-Azidoethoxy)-2-(2-bromoethoxy)ethane |
| CAS | 530151-56-5 |
1-(2-Azidoethoxy)-2-(2-bromoethoxy)ethane - Physico-chemical Properties
| Molecular Formula | C6H12BrN3O2 |
| Molar Mass | 238.08238 |
| Storage Condition | -20°C |
| In vitro study | ADCs are comprised of an antibody to which is attached an ADC cytotoxin through an ADC linker. PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins. |
1-(2-Azidoethoxy)-2-(2-bromoethoxy)ethane - Preparation solution concentration reference
| 1mg | 5mg | 10mg | |
|---|---|---|---|
| 1 mM | 4.2 ml | 21.001 ml | 42.002 ml |
| 5 mM | 0.84 ml | 4.2 ml | 8.4 ml |
| 10 mM | 0.42 ml | 2.1 ml | 4.2 ml |
| 5 mM | 0.084 ml | 0.42 ml | 0.84 ml |
Last Update：2024-01-02 23:10:35
1-(2-Azidoethoxy)-2-(2-bromoethoxy)ethane - Reference Information
| biological activity | Bromo-PEG2-C2-azide is a non-degradable ADC linker for the synthesis of antibody-conjugated drugs (ADCS). Bromo-PEG2-C2-azide is also a PEG-based PROTAC linker and can be used in the synthesis of PROTAC. |
Last Update：2024-04-10 22:29:15
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