1-(2-Bromoethyl)-4-Nitrobenzene
4-Nitrophenethyl Bromide
CAS: 5339-26-4
Molecular Formula: C8H8BrNO2
1-(2-Bromoethyl)-4-Nitrobenzene - Names and Identifiers
1-(2-Bromoethyl)-4-Nitrobenzene - Physico-chemical Properties
| Molecular Formula | C8H8BrNO2 |
| Molar Mass | 230.06 |
| Density | 1.6270 (rough estimate) |
| Melting Point | 67-69 °C (lit.) |
| Boling Point | 116°C/0.2mm |
| Flash Point | 116°C/0.2mm |
| Water Solubility | Soluble in water (partly) and methanol. |
| Solubility | Chloroform(Slightly), Dichloromethane (Slightly), Methanol (Slightly) |
| Vapor Presure | 0.00115mmHg at 25°C |
| Appearance | Adhering Crystals or Crystalline Powder |
| Color | Yellow |
| BRN | 1909321 |
| Storage Condition | Sealed in dry,Room Temperature |
| Refractive Index | 1.6120 (estimate) |
| Physical and Chemical Properties | Slightly yellow solid. |
1-(2-Bromoethyl)-4-Nitrobenzene - Risk and Safety
| Hazard Symbols | Xi - Irritant |
| Risk Codes | R36/37/38 - Irritating to eyes, respiratory system and skin. R43 - May cause sensitization by skin contact |
| Safety Description | S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. S36/37 - Wear suitable protective clothing and gloves. S24/25 - Avoid contact with skin and eyes. |
| WGK Germany | 3 |
| HS Code | 29049085 |
| Hazard Note | Irritant |
1-(2-Bromoethyl)-4-Nitrobenzene - Reference Information
| NIST chemical information | Information provided by: webbook.nist.gov (external link) |
| use | 4-nitrophenyl ethyl bromide is an important fine chemical product. because there are easily reactive functional groups such as nitro, halogen and benzene ring in the molecule, it is widely used in medicine, dyes and other fields. The demand of enterprises is strong and has a good market prospect. |
| synthesis method | 4-nitrophenylethyl bromide was synthesized from β-bromophenane with acetic acid, acetic anhydride and fuming nitric acid as nitrating agents. The effect of reaction conditions on product yield was investigated experimentally. Experiments show that the suitable reaction conditions are: the reaction temperature is controlled at -5 ℃, 0.15mol of fuming nitric acid and 0.12mol of acetic anhydride are needed to 0.1mol of β-bromophenylethane, the reaction time is 4 hours, and the yield of 4-nitrophenylethyl bromide is 69.2%. |
Last Update：2024-04-09 21:04:16
