1-(2-C-Methyl-β-D-ribofuranosyl)cytosine
2'-C-Methylcytidine
CAS: 20724-73-6
Molecular Formula: C10H15N3O5
1-(2-C-Methyl-β-D-ribofuranosyl)cytosine - Names and Identifiers
| Name | 2'-C-Methylcytidine |
| Synonyms | NM-107 VALOPICITABINE -C-Methylcytidine 2''-METHYLCYTIDINE 2'-C-METHYLCYTIDINE 2'-C-Methylcytidine 2'-CMethyl-D-cytidine cytidine, 2'-C-methyl- 2'-C-Methyl-1-β-D-ribofuranosylcytosine 1-(2-C-Methyl-β-D-ribofuranosyl)cytosine |
| CAS | 20724-73-6 |
| EINECS | 200-001-2 |
| InChI | InChI=1/C10H15N3O5/c1-10(17)7(15)5(4-14)18-8(10)13-3-2-6(11)12-9(13)16/h2-3,5,7-8,14-15,17H,4H2,1H3,(H2,11,12,16)/t5-,7-,8-,10-/m1/s1 |
| InChIKey | PPUDLEUZKVJXSZ-VPCXQMTMSA-N |
1-(2-C-Methyl-β-D-ribofuranosyl)cytosine - Physico-chemical Properties
| Molecular Formula | C10H15N3O5 |
| Molar Mass | 257.24 |
| Density | 1.72±0.1 g/cm3(Predicted) |
| Melting Point | 243-245°C |
| Boling Point | 523.9±60.0 °C(Predicted) |
| Flash Point | 270.7°C |
| Solubility | H2O: >20mg/mL |
| Vapor Presure | 3.63E-13mmHg at 25°C |
| Appearance | powder |
| Color | white to off-white |
| pKa | 13.53±0.70(Predicted) |
| Storage Condition | -20°C |
| Refractive Index | 1.699 |
| In vitro study | NM107 (25 μM; 24 hours; Huh7-1 cells and cell culture-propagated HCV) treatment decreases extracellular viral titers and intracellular RNA levels. RT-PCR Cell Line: Huh7-1 cells and cell culture-propagated HCV (HCVcc) Concentration: 25 μM Incubation Time: 24 hours Result: Extracellular virus titers declined in parallel with intracellular RNA levels. |
1-(2-C-Methyl-β-D-ribofuranosyl)cytosine - Risk and Safety
| Hazard Symbols | Xi - Irritant |
| Risk Codes | 36/37/38 - Irritating to eyes, respiratory system and skin. |
| Safety Description | 26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. |
| WGK Germany | 3 |
1-(2-C-Methyl-β-D-ribofuranosyl)cytosine - Preparation solution concentration reference
| 1mg | 5mg | 10mg | |
|---|---|---|---|
| 1 mM | 3.887 ml | 19.437 ml | 38.874 ml |
| 5 mM | 0.777 ml | 3.887 ml | 7.775 ml |
| 10 mM | 0.389 ml | 1.944 ml | 3.887 ml |
| 5 mM | 0.078 ml | 0.389 ml | 0.777 ml |
Last Update：2024-01-02 23:10:35
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Product Name: 2'-C-Methylcytidine Visit Supplier Webpage Request for quotationCAS: 20724-73-6
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Mobile: 18021002903
QQ: 3008007409
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